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Investigation of the Blood Glucose Lowering Potential of the Jamaican Momordica charantia (Cerasee) Fruit in Sprague-Dawley Rats

Issue: 
DOI: 
10.7727/wimj.2014.093
Pages: 
315–9
Synopsis: 
The blood glucose lowering potential of aqueous fruit extracts of the Jamaican plant species (Momordica charantia) was investigated in Sprague-Dawley rats. The extract showed no hypoglycaemic or antidiabetic activity. However, there was improvement in glucose tolerance of glucose-primed normoglycaemic rats during oral glucose tolerance test.

ABSTRACT

Accepted: 
23 Apr, 2014
PDF Attachment: 
Journal Sections: 
Journal Authors: 
e-Published: 29 Apr, 2015

Evaluation of the Hypoglycaemic Activity of Petiveria alliacea (Guinea Hen Weed) Extracts in Normoglycaemic and Diabetic Rat Models

Issue: 
DOI: 
10.7727/wimj.2013.142
Synopsis: 
The aqueous and hexane extracts of Petiveria alliacea were investigated for hypoglycaemic properties in normoglycaemic and streptozotocin-induced diabetic rats. The findings demonstrated no significant changes in blood glucose levels in response to Petiveria alliacea treatment.

ABSTRACT

Objective: Petiveria alliacea (P alliacea) has ethno-traditional use as a hypoglycaemic agent in Jamaica and is yet to be scientifically validated as such.  Therefore, extracts of aerial parts of the plant were evaluated for hypoglycaemic activity in normoglycaemic and diabetic rats.

Revised: 
20 Sep, 2013
Accepted: 
27 Sep, 2013
PDF Attachment: 
Journal Sections: 
Journal Authors: 
e-Published: 18 Feb, 2014

Pre-published Manuscript

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In the pre-published stage, this manuscript may contain statements, opinions, and information that have errors in facts, figures, or interpretation. Any final changes in this manuscript will be made at the time of publication and will be reflected in the final electronic version of the issue. The editors and authors and their respective employees are not responsible or liable for the use of any such inaccurate or misleading data, opinion or information contained in the articles in this section.

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