A Frontiers of Science meeting between The Royal Society and The University of the West Indies will be held this week, March 19-21 at Chicheley Hall, UK. This is the inaugural meeting in a three year programme for the advancement of science in the Caribbean and the use of science to solve big problems affecting the Region. The programme was crafted through 2 years of consultations between UWI Solutions for Developing Countries (UWI SODECO) and The Royal Society.