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B Aktan

Vascular Endothelial Dysfunction Caused by Oxidative Stress is a Predictor Factor for Complications of Obstructive Sleep Apnea Syndrome

DOI: 
10.7727/wimj.2015.383
Synopsis: 
We aimed to determine oxidative imbalance and vascular endothelial dysfunction as suspects for complications of OSAS. We found both oxidative stress and vascular endothelial dysfunction lead to early development of atherosclerosis which may cause the life-threatening complications of OSAS.

ABSTRACT

Objective: Obstructive sleep apnea syndrome (OSAS) is characterized by repetitive episodes of upper airway obstruction that occur during sleep which leads to cardiovascular, neurovascular and metabolic diseases. The mechanisms of complications in these patients are unclear. In this report, we aimed to determine the cause of oxidative imbalance in patients with OSAS and to evaluate the vascular endothelial dysfunction as a suspect for complications of the disease.

Accepted: 
10 Sep, 2015
Journal Sections: 
e-Published: 15 Feb, 2016

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Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

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