HIC Lowe

The Anti-cancer Activity of Vernonia divaricata Sw against Leukaemia, Breast and Prostate Cancers In Vitro

Issue:

Vol 63, Issue 4: Aug (2014)

DOI:

10.7727/wimj.2013.232

Pages:

285–8

Synopsis:

The crude hexane and methanol extracts of V divaricata exhibited anti-proliferation activity and as such, it is a potential drug for cancer chemotherapy and prevention.

ABSTRACT

Background: Vernonia divaricata is one of five endemic Vernonia species of Jamaica. The ethno-medicinal uses of other species have been established, however, scientific validation of this species has not yet been done and as such this paper is aimed at identifying the anti-cancer activity of V divaricata against leukaemia, breast and prostate cancer cell lines.

Received:

14 Aug, 2013

Accepted:

16 Oct, 2013

PDF Attachment:

lowe_et_al-anti-cancer_activity_of_vernonia_divaricata_against_cancer.pdf

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e-Published: 21 Jul, 2014

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In vitro and In vivo Anti-cancer Effects of Tillandsia recurvata (Ball Moss) from Jamaica

Issue:

Vol 62, Issue 3: Mar (2013)

DOI:

10.7727/wimj.2013.091

Pages:

177–80

Synopsis:

The anti-cancer activity of Tillandsia recurvata was evaluated. The crude extract demonstrated anti-proliferation activity, killing > 50% of the cells at a concentration of 2.5 μg/ml. Kaposi sarcoma tumours were inhibited by 75% compared to control in vivo (p < 0.05).

ABSTRACT

Objective: Tillandsia recurvata, also commonly known as Ball Moss, is endemic to Jamaica and some parts of the Caribbean and South America. The plant, despite being reported to be used in folk medicine, had not previously been evaluated for its anti-cancer potential. The aim of this study was to evaluate the anti-cancer activity of Ball Moss.

Received:

10 Apr, 2013

Accepted:

23 Apr, 2013

PDF Attachment:

dr_hic_lowe_wimj_march.qxd_.pdf

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