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Oesophageal Carcinoma in Jamaica, 1978–2007: Histological Distribution and Trends in Incidence

DOI: 
10.7727/wimj.2018.015
Pages: 
Synopsis: 
The incidence of oesophageal squamous cell carcinoma in Jamaica has been decreasing in both genders. Oesophageal adenocarcinoma incidence has been increasing in males, but, unlike data reported elsewhere, has been decreasing in females. Investigation into risk factors for oesophageal adenocarcinoma in Jamaica is warranted

 

ABSTRACT

Objectives: To investigate the trends in incidence and histological distribution of oesophageal carcinoma in Kingston and St Andrew (KSA), Jamaica, over the 30-year period 1978‒2007.

Accepted: 
08 May, 2018
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Journal Sections: 
e-Published: 26 Feb, 2019

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

NKILA: A New LncRNA Regulates the Pro-inflammation Functions of NF-κB

DOI: 
10.7727/wimj.2015.541
Synopsis: 
Abnormal activation of NF-κB signalling pathway plays a crucial role in cancer inflammation. In Cancer Cell, Liu et al, identify a novel lncRNA, NKILA, that is a negative feedback regulator of NF-κB, thus represses NF-κB signalling and cancer-associated inflammation.

INTRODUCTION

Accepted: 
16 Nov, 2015
PDF Attachment: 
Journal Sections: 
Journal Authors: 
e-Published: 01 Apr, 2016

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

An Audit of Haematology/Oncology Clinic Services at an Urban Academic Hospital in Jamaica

Issue: 
DOI: 
10.7727/wimj.2013.329
Pages: 
511-14
Synopsis: 
The Haematology/oncology Clinic is a clinical training unit of the University Hospital of the West Indies, and serves patients with a wide range of disorders. In this study, the types of disorders seen were explored, and recommendations put forward for expansion of cancer care and supportive services.

ABSTRACT

Objective: To determine the range of disorders seen at the Haematology/oncology Clinic of the University Hospital of the West Indies (UHWI), and the proportion of Oncology referrals to the clinic.

Revised: 
28 Apr, 2015
Accepted: 
30 Apr, 2015
PDF Attachment: 
Journal Sections: 
e-Published: 11 Mar, 2016

Urinary Advanced Oxidation Protein Product: A Potential Oxidative Damage Marker for Cancer

Issue: 
DOI: 
10.7727/wimj.2012.324
Pages: 
505-10
Synopsis: 
The urinary oxidative protein damage in cancer is significantly higher than diabetes mellitus (with and without hypertension) and may potentially serve as a non-invasive oxidative biomarker for cancer.

ABSTRACT

Revised: 
03 Jun, 2015
Accepted: 
10 Aug, 2015
PDF Attachment: 
Journal Sections: 
e-Published: 09 Mar, 2016

DNA Release and Uptake Associated with the Development of Pleomorphic Cells in Mammalian Skin Autotransplants

Issue: 
Pages: 
257–62
Synopsis: 
DNA release and uptake in an in vivo mammalian system is described for the first time, and is related to normal growth and differentiation, abnormal growth and cancer. It is proposed that there is a homeostatic exchange system of intercellular factors including genetic material (DNA/RNA) between cells and tissues, important for growth and differentiation. Disturbances of the messages or the homeostatic control of the exchange system can result in abnormal growth and cancer.

ABSTRACT

Objective: Although several in vitro studies have demonstrated active release of DNA by living cells, there is still doubt. There are no such in vivo studies (1). The following experiment is an in vivo study to determine whether DNA release and uptake by cells and tissues occur and can be related to normal growth and differentiation, abnormal growth and cancer.

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Journal Authors: 
e-Published: 29 Jan, 2014

Expression of Low Molecular Weight Proteins in Patients with Leukaemia

Issue: 
Pages: 
235–9
Synopsis: 
This study was conducted to observe the differences in the level of low molecular weight proteins in the sera of patients with leukaemia in comparison to healthy subjects. The sera of patients with leukaemia showed 15 peaks in the densitometric curve in comparison to the seven peaks of the controls; eight protein fractions appeared in the experimental groups and not in the control group.

ABSTRACT

PDF Attachment: 
Journal Sections: 
e-Published: 21 Aug, 2013

Trends in Incidence and Age Distribution of Oral Cavity and Oropharyngeal Squamous Cell Carcinomas, Kingston and St Andrew, Jamaica, 1978–2007

Issue: 
DOI: 
10.7727/wimj.2013.164
Pages: 
128–33
Synopsis: 
The incidence rates of tongue and tonsillar cancers have been decreasing in Jamaica but continue to predominate among older men. This is unlike data reported elsewhere, where rates have been increasing in young adults, and therefore warrants further study.
ABSTRACT
 
Objective: Several countries have reported increasing incidence of oral cavity and oropharyngeal (OCOP) squamous cell carcinoma (SCC) over recent years, particularly among young men and primarily in tongue and tonsil subsites, attributed to human papillomavirus (HPV) infection. This study examines trends in incidence and age distribution of OCOP SCC in Jamaica over a 30-year period.
 
Accepted: 
24 Jun, 2013
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Journal Sections: 
e-Published: 11 Apr, 2014

In vitro and In vivo Anti-cancer Effects of Tillandsia recurvata (Ball Moss) from Jamaica

Issue: 
DOI: 
10.7727/wimj.2013.091
Pages: 
177–80
Synopsis: 
The anti-cancer activity of Tillandsia recurvata was evaluated. The crude extract demonstrated anti-proliferation activity, killing > 50% of the cells at a concentration of 2.5 μg/ml. Kaposi sarcoma tumours were inhibited by 75% compared to control in vivo (p < 0.05).

ABSTRACT

Objective: Tillandsia recurvata, also commonly known as Ball Moss, is endemic to Jamaica and some parts of the Caribbean and South America. The plant, despite being reported to be used in folk medicine, had not previously been evaluated for its anti-cancer potential. The aim of this study was to evaluate the anti-cancer activity of Ball Moss.

Accepted: 
23 Apr, 2013
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Journal Sections: 
Journal Authors: 
e-Published: 26 Jun, 2013

Herbal Medicine Use among Puerto Rican Cancer Patients

DOI: 
10.7727/wimj.2016.124
Synopsis: 
Puerto Rican islanders have a rich tradition of herbal use for curing different malignancies. However, little is known about herbal use and cancer among this population. Our research shows sociodemographic characteristics correlating to herbal medicine use.

ABSTRACT

Accepted: 
30 Jun, 2016
PDF Attachment: 
Journal Sections: 
e-Published: 18 Jul, 2016

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Colon Cancer Screening

Issue: 
Pages: 
365–7

INTRODUCTION

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Journal Authors: 
e-Published: 17 Jun, 2013

Pages

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