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J Yang

Extracellular Superoxide Dismutase, a Potential Extracellular Biomarker Candidate for Prolactinoma

Issue: 
DOI: 
Doi:10.7727/wimj.2012.213
Pages: 
665–9
Synopsis: 
Extracellular superoxide dismutase (EC-SOD) is an extracellular protein and serum EC-SOD could be a good candidate for the diagnosis of prolactinoma. There is a positive relationship between prolactinoma severity and EC-SOD.

ABSTRACT

Aim: To investigate whether the extracellular superoxide dismutase (EC-SOD) and manganese superoxide dismutase (Mn-SOD) level changes during prolactinoma (PRL) development.

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Journal Sections: 
e-Published: 01 Mar, 2013

Extracellular Superoxide Dismutase, a Potential Extracellular Biomarker Candidate for Prolactinoma

DOI: 
Doi:10.7727/wimj.2012.213

Aim: To investigate whether the extracellular superoxide dismutase (EC-SOD) and manganese superoxide dismutase (Mn-SOD) level changes during prolactinoma (PRL) development.

Methods: Surgical tissues from 37 female patients with PRL were tested for Mn-SOD and serum sample from such PRL patients were tested for EC-SOD level changes with Western Blot. The Mn-SOD level from blood cells was also investigated to show whether the Mn-SOD variation can locate tumorigenesis tissues.

PDF Attachment: 
Journal Sections: 
e-Published: 15 Feb, 2013

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