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JAMA Tan

Chelation Therapy with Desferrioxamine does not Normalize Ferritin Level but Attenuates Oxidative Damage and Improves Total Antioxidant Level in Malaysian Chinese β-thalassaemia Major Patients

Issue: 
Pages: 
3–8
Synopsis: 
Beta-thalassaemia major patients require monthly blood transfusions. Studies on the oxidant-antioxidant indices in patients on desferrioxamine-chelation or without chelation indicate that desferrioxamine chelation does not normalize ferritin level but attenuates oxidative damage and improves total antioxidant level in these patients.

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e-Published: 17 Oct, 2013

Paraoxonase 1 Status in Keratoconus: A Preliminary Study of Activity and Polymorphism

Issue: 
DOI: 
10.7727/wimj.2011.044
Pages: 
569–73
Synopsis: 
Keratoconic patients have reduced paraoxonase activity, which suggests that keratoconic corneas are more susceptible to oxidative stress. Reduced paraoxonase activity and keratoconus status appear to be associated with ethnicity.

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e-Published: 24 Jan, 2013
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