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M Gossell-Williams

Gentamicin Therapeutic Drug Monitoring: Importance in the Hospital Setting

Issue: 
DOI: 
10.7727/wimj.2015.603
Pages: 
324–8
Synopsis: 
Gentamicin has a propensity to induce nephrotoxicity. This study showed that most of the patients treated with gentamicin experienced some levels of nephrotoxicity and suggests the need for the vigilant monitoring of serum creatinine in such patients in a hospital setting without therapeutic drug monitoring facilities.

ABSTRACT

Background: Use of gentamicin places patients at risk of developing drug-induced nephrotoxicity, requiring special consideration to be given to serum creatinine monitoring and therapeutic drug monitoring (TDM).

Objectives: To evaluate the prevalence of nephrotoxicity without the availability of TDM.

Accepted: 
02 Feb, 2016
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Journal Sections: 
e-Published: 31 Mar, 2016

The Use of Analgesic Drugs in Patients with Sickle Cell Painful Crisis

Issue: 
DOI: 
10.7727/wimj.2012.272
Pages: 
479–83
Synopsis: 
Painful crisis in patients with sickle cell anaemia is associated with severe pain in 75% and most will require second line therapy for adequate resolution. Physicians need to provide adequate pain relief to decrease morbidity in these patients.

ABSTRACT

Objective: To determine the drug options used for pain in patients with acute sickle cell painful crisis at the University Hospital of the West Indies (UHWI), Jamaica.

Method: This retrospective study assessed all patients admitted to the UHWI between January 1, 2006 and December 31, 2010 with acute sickle cell anaemia painful crisis and the data obtained regarding site, severity, outcome and drug options selected for pain.

Revised: 
24 Feb, 2013
Accepted: 
12 Mar, 2013
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Journal Sections: 
e-Published: 30 Apr, 2014

Monoclonal Antibodies in Cancer Therapy: Mechanisms, Successes and Limitations

Issue: 
DOI: 
10.7727/wimj.2013.241
Pages: 
650–4
Synopsis: 
The classification, efficacy and significantly reduced toxicity of chemotherapeutic monoclonal antibodies (CmAbs) available for use in the United States of America are presented, and their limitations and future considerations are explored.

ABSTRACT

Accepted: 
24 Feb, 2014
PDF Attachment: 
Journal Sections: 
e-Published: 29 May, 2014

Preference of Patient Information Leaflets over Standard Drug Monographs by Patients Prescribed Hydrochlorothiazide, Nifedipine and Enalapril

Issue: 
Pages: 
271–9
Synopsis: 
There is benefit in designing patient information leaflets that simplify language and medication information contained in standard drug monographs, including better understanding of precautions to take while on medication and when to consult physicians.

ABSTRACT

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e-Published: 21 Aug, 2013

REVIEW ARTICLE: The Past and Present Use of Plants for Medicines

Issue: 

INTRODUCTION

In early civilizations, illness was usually believed to be due to divine punishment. The Aztecs Indian of South America, for example, believed that particular diseases were linked to specific gods; thus their god Tlaloc was associated with diseases caused by water, such as oedema (4). Similarly, Greek physicians, such as Theoprastus, were generally followers of Asclepius, the god of Medicine. Thus the use of plants for healing became strongly associated with the gods.

PDF Attachment: 
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e-Published: 10 Jun, 2013

Pre-published Manuscript

This manuscript has been assigned to a volume and issue but has not yet been published. It is either being edited, typeset or is in the proof stage of publication.
In the pre-published stage, this manuscript may contain statements, opinions, and information that have errors in facts, figures, or interpretation. Any final changes in this manuscript will be made at the time of publication and will be reflected in the final electronic version of the issue. The editors and authors and their respective employees are not responsible or liable for the use of any such inaccurate or misleading data, opinion or information contained in the articles in this section.

Choline Supplementation Facilitates Short-term Memory Consolidation into Intermediate Long-term Memory of Young Sprague-Dawley Rats

Issue: 
Pages: 
4–8
Synopsis: 
We examined the effects of choline supplementation in young Sprague-Dawley rats. Rats were place into two groups and received either choline supplementation or vehicle over a period of two weeks. We found that the two-week choline supplementation in young rats improved the consolidation of short-term memory into intermediate long-term memory.

ABSTRACT

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e-Published: 06 Jun, 2013

Dietary Intake of Choline and Plasma Choline Concentrations in Pregnant Women in Jamaica

Issue: 
Pages: 
355–9
Synopsis: 
We examined the plasma choline concentration of sixteen women attending the antenatal clinic of the University Hospital of the West Indies and found that their fasting choline concentrations were low to normal. This may be a reflection of low choline dietary intake.

ABSTRACT

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e-Published: 06 Jun, 2013

A Review of Pharmacovigilance

Issue: 
DOI: 
10.7727/wimj.2013.251
Pages: 
771–4
Synopsis: 
Spontaneous reporting of adverse drug reactions (ADRs) is an essential component of pharmacovigilance, but the safe and appropriate use of drugs is limited by under-reporting of ADRs. Knowledge of pharmacovigilance could form the basis for interventions aimed at improving reporting rates.

ABSTRACT

Pharmacovigilance supports safe and appropriate use of drugs. Spontaneous reporting of adverse drug reactions (ADRs) is an essential component of pharmacovigilance. However, there is significant underreporting of ADRs. Adverse drug reactions have become a major problem in developing countries. Knowledge of pharmacovigilance could form the basis for interventions aimed at improving reporting rates and decreasing ADRs.

Accepted: 
27 Sep, 2013
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e-Published: 05 Mar, 2015

The Antimicrobial Screening of a Barbadian Medicinal Plant with Indications for Use in the Treatment of Diabetic Wound Infections

Issue: 
DOI: 
10.7727/wimj.2011.223
Pages: 
861–4
Synopsis: 
This article highlights the investigation of the antimicrobial activity of the plant Justicia secunda, and it seeks to promote the need for further research efforts in the discovery of novel antimicrobial agents from medicinal plants.

ABSTRACT

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e-Published: 24 Jun, 2013

The Antimicrobial Screening of a Barbadian Medicinal Plant with Indications for Use in the Treatment of Diabetic Wound Infections

DOI: 
10.7727/wimj.2011.223

ABSTRACT

PDF Attachment: 
Journal Sections: 
e-Published: 20 Feb, 2013

Pre-published Manuscript

This manuscript has been assigned to a volume and issue but has not yet been published. It is either being edited, typeset or is in the proof stage of publication.
In the pre-published stage, this manuscript may contain statements, opinions, and information that have errors in facts, figures, or interpretation. Any final changes in this manuscript will be made at the time of publication and will be reflected in the final electronic version of the issue. The editors and authors and their respective employees are not responsible or liable for the use of any such inaccurate or misleading data, opinion or information contained in the articles in this section.

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