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Trona Causes Fetal Loss in Pregnant Rat via an Oestrogen-dependent Mechanism

Issue: 
DOI: 
10.7727/wimj.2014.254
Pages: 
83–6
Synopsis: 
The study demonstrated that trona causes fetal loss. This could be attributed to the chemical constituents especially sodium and calcium. This effect is possibly via oestrogen-dependent mechanism. This study mainly focussed on the potentials of trona to cause fetal loss and its associated mechanism.

ABSTRACT

 

Background: There is a claim in folklore medicine in Nigeria that trona (a sesquicarbonate or hydrated carbonate of sodium) causes fetal loss. However, this has not been substantiated or refuted by any scientific evidence.

Aim: This study evaluates whether or not trona causes fetal loss in pregnant female Wistar rats.

Accepted: 
31 Oct, 2014
PDF Attachment: 
Journal Sections: 
Journal Authors: 
e-Published: 06 May, 2015
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