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HaCaT keratinocytes

Site-directed Mutagenesis (Y52E) of POLH Affect Its Ability to Bypass Ultraviolet-induced DNA Lesions in HaCaT Cells

Issue: 
Vol 63, Issue 4: Aug (2014)
DOI: 
10.7727/wimj.2014.063
Pages: 
307–11
Synopsis: 
Site-directed mutagenesis (Y52E) of POLH has reduced capacity to bypass ultraviolet-induced DNA lesions in HaCaT cells.

ABSTRACT

Received: 
17 Mar, 2014
Accepted: 
27 Mar, 2014
PDF Attachment: 
PDF icon luo_et_al-polh_mutation_in_hacat_cells.pdf
Journal Sections: 
Original Articles
Keywords: 
DNA lesion bypass
DNA polymerase η
HaCaT keratinocytes
mutation
ultraviolet
Journal Authors: 
C Luo
Z Chen
Q He
K Cao
S Wang
J Liu
R Liu
J Zhou
e-Published: 22 Apr, 2014
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West Indian Medical Journal

Faculty of Medical Sciences,
The University of the West Indies,
Mona, Kingston 7
Tel: (876) 927-1214
Fax: (876) 927-1846
wimj@uwimona.edu.jm
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