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methadone

QT Interval Prolongation Associated with Azithromycin/Methadone Combination

Issue: 
DOI: 
10.7727/wimj.2012.162
ABSTRACT
 
This report documents the occurrence of QT prolongation in a 57-year old man, on methadone replacement therapy, treated with azithromycin for community acquired pneumonia. This case highlights a hitherto unknown drug interaction. In light of ever-increasing use of azithromycin, it is imperative that azithromycin be used with caution in patients who are already on drugs that are known to cause QT prolongation or that cause torsades de pointes.
Accepted: 
29 Aug, 2012
PDF Attachment: 
Journal Sections: 
e-Published: 20 Feb, 2014

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