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omeprazole

Effect of Clopidogrel with or without Omeprazole in Patients with Carotid Artery Stenting

Issue: 
DOI: 
10.7727/wimj.2012.041
Pages: 
135–9
Synopsis: 
In our small study, patients with carotid artery stent placement who received dual antiplatelet therapy had a significant reduction in gastrointestinal bleeding with omeprazole use when compared to those without omeprazole. There was also no effect of concomitant use of omeprazole and clopidogrel on antiplatelet inhibition.

ABSTRACT

Background: Recent concerns have been raised about the potential for proton pump inhibitors (PPIs) to blunt the efficacy of clopidogrel. We observed the effect of clopidogrel plus aspirin with or without omeprazole in patients with carotid stenoses after they received placement of carotid stents.

Accepted: 
27 Mar, 2012
PDF Attachment: 
Journal Sections: 
Journal Authors: 
e-Published: 16 May, 2013
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