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rotavirus vaccine

Rotavirus Vaccine Trial in Jamaica

Issue: 
Pages: 
405–7
Synopsis: 
Rotaviruses have been a significant cause of dehydrating gastroenteritis, contributing to infant morbidity and mortality in Jamaica. We enrolled 1804 Jamaican infants in the international randomized, placebo-controlled, pentavalent (G1, G2, G3, G4 and P1) rotavirus vaccine trial. This pentavalent vaccine was found to significantly reduce rotavirus-attributable emergency room visits and hospitalizations, without increasing the rates of intussusception or other serious adverse events in Jamaican infants.

ABSTRACT

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e-Published: 21 Aug, 2013
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