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Meningo-encephalo-myelitis in Children during the Zika Virus Epidemic in Grenada

DOI: 
10.7727/wimj.2017.227

ABSTRACT

Accepted: 
18 Dec, 2017
Journal Sections: 
e-Published: 20 Dec, 2017

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Trends of Microcephaly and Severe Arthrogryposis in Three Urban Hospitals following the Zika, Chikungunya and Dengue Fever Epidemics of 2016 in Jamaica

Issue: 
DOI: 
10.7727/wimj.2017.124
Pages: 
10–9
Synopsis: 
Newborns with the characteristics of congenital syndrome associated with Zika virus (CSAZ) are being born in urban hospitals after the 2016 Zika virus epidemic in Jamaica. Phenotypic features include microcephaly, craniofacial disproportion, neuro-imaging and neuro-pathological findings and arthrogryposis. A trend towards babies being delivered with small head circumferences, but not yet in the range of microcephaly and others with normal head sizes who were born to women who were symptomatic in pregnancy is also being observed. While, most babies with probable CSAZ are being born to asymptomatic women who did not report any symptoms related to arbovirus illness in pregnancy. Diagnosis is challenged by serological cross-reactivity between circulating flaviviruses. Team management is multidisciplinary to maximize the neuro-developmental potential of this vulnerable patient population.
ABSTRACT
 
Introduction: Jamaica experienced its maiden Zika virus (ZIKV) epidemic in 2016, while dengue (serotypes 3 and 4) and chikungunya were also circulating.
 
Aim: We describe initial trends in microcephaly and arthrogryposis observed by the clinicians from three urban birthing facilities during late 2016 to early 2017.
Accepted: 
12 Jun, 2017
PDF Attachment: 
Journal Sections: 
e-Published: 12 Jun, 2017

Chikungunya in Jamaica – Public Health Effects and Clinical Features in Children

Issue: 
DOI: 
10.7727/wimj.2016.529
Pages: 
431-37
Synopsis: 
The Chikungunya Fever epidemic had significant public health and economic impact in Jamaica. In children, there were characteristic presentations in neonates and young infants and in children six months to six years. Neurologic involvement was common but other organ dysfunction was rare.

ABSTRACT

Background: Chikungunya virus entered the Caribbean for the first time in 2013 and Jamaica experienced its maiden epidemic with Chikungunya Fever in 2014. We aimed to describe the public health effects and describe the clinical features in children and adolescents in Jamaica.

Accepted: 
26 Oct, 2016
PDF Attachment: 
Journal Sections: 
e-Published: 26 Oct, 2016

Outcome of Dengue in Hospitalized Jamaican Children

Issue: 
DOI: 
10.7727/wimj.2016.525
Pages: 
442-49
Synopsis: 
Before the emergence of Zika in 2016 and Chikungunya in 2014, there have been numerous dengue outbreaks in the Caribbean. Despite this, there is a paucity of published studies on dengue in children from this region. The potential for exponential spread of the Aedes aegypti dengue vector and its deleterious outcomes in children underlines the importance of this paper.

ABSTRACT

Background: Dengue fever is hyper-endemic in Jamaica with exponential rates of infection in successive outbreaks. The absence of local data and the potential for massive outbreaks in a country where a third of the population are children formed the basis for this study. 

Accepted: 
26 Oct, 2016
PDF Attachment: 
Journal Sections: 
e-Published: 26 Oct, 2016

Acute Paralysis and Neuro-inflammation in Jamaican Children during Zika virus and Dengue Epidemics of 2016

Issue: 
DOI: 
10.7727/wimj.2016.526
Pages: 
425-30
Synopsis: 
This case series suggests a unique clinical pattern of neuro-inflammation in Jamaican adolescents occurring during the ZIKV epidemic and questions the role of the three circulating arboviruses in the pathogenesis.

ABSTRACT

Accepted: 
24 Oct, 2016
PDF Attachment: 
Journal Sections: 
e-Published: 25 Oct, 2016

Emergence of Zika Virus Epidemic and the National Response in Jamaica

Issue: 
DOI: 
10.7727/wimj.2016.488
Pages: 
243–9
Synopsis: 
The Zika virus epidemic in Jamaica is evolving and includes cases of Guillain-Barré Syndrome and reports in pregnant women. Zika may become endemic in Jamaica, similar to dengue and chikungunya. Safe and effective dengue, chikungunya fever and ZIKV vaccines are needed to mitigate the devastating effects of these three diseases.

ABSTRACT

Background: Jamaica, along with the Americas, experienced major epidemics of arboviral diseases transmitted by the Aedes aegypti mosquito in recent years. These include dengue fever in 2012, chikungunya fever in 2014 and Zika virus infection (ZIKV) in 2016. We present the emergence of the ZIKV epidemic in Jamaica and outline the national response.

Accepted: 
28 Sep, 2016
PDF Attachment: 
Journal Sections: 
e-Published: 26 Sep, 2016

Unravelling the Paediatric and Perinatal Zika Virus Epidemic through Population-based Research

Issue: 
DOI: 
10.7727/wimj.2016.454
Pages: 
239–42
Synopsis: 
Zika virus causes Guillain-Barre Syndrome and microcephaly. Clinical and laboratory diagnosis is complicated. Population-based research can elucidate ZIKV epidemiology, vertical transmission, fetal risks of maternal ZIKV infection and natural history of congenital and non-congenital ZIKV infection provided by the activities in “ZIKAction” research consortium, recently funded by the European Commission.

ABSTRACT

Accepted: 
23 Aug, 2016
PDF Attachment: 
Journal Sections: 
Journal Authors: 
e-Published: 19 Sep, 2016

Professor Emeritus Richard Williams Olmsted

Issue: 
Pages: 
394–5
 Professor Emeritus Richard Williams Olmsted
Department of Child Health, The UWI, Mona and Psychiatrist, Ministry of Health, Jamaica
  June 27, 1920 – March 8, 2013
PDF Attachment: 
Journal Sections: 
Journal Authors: 
e-Published: 13 Jun, 2014

Conjoined Twins: Bioethics, Medicine and the Law

Issue: 
Pages: 
123–24
Synopsis: 
Clinicians managing conjoined twins find themselves at a crossroad where bioethics, medicine and law converge.
INTRODUCTION
 
PDF Attachment: 
Journal Sections: 
e-Published: 06 Feb, 2014

The “Missed” Population of Perinatally HIV-infected Adolescent Slow Progressors in Jamaica

Issue: 
Pages: 
295–7

INTRODUCTION

PDF Attachment: 
Journal Sections: 
e-Published: 17 Jun, 2013

Pages

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