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asthma

Impaired Bronchoprotection Is Not Induced by Increased Smooth Muscle Mass in Chronic Treatment In Vivo with Formoterol in Asthmatic Mouse Model

Issue: 
DOI: 
10.7727/wimjopen.2014.177
Pages: 
78–83
Synopsis: 
Compelling evidence proves that bronchial smooth muscle mass significantly increases in asthmatics, and chronic formoterol administration induces impaired bronchoprotection. No significant difference was detected in increased smooth muscle mass, implying that some other molecular mechanisms might be involved.

ABSTRACT

Accepted: 
August 11, 2014
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Journal Sections: 

Effect of 1,25-Dihydroxy Vitamin D3 on the Expression of Interleukin-17 and -21 in an Asthma Mice Model

Issue: 
DOI: 
10.7727/wimjopen.2015.161
Pages: 
115–20
Synopsis: 
Bronchial asthma is a common respiratory disease. This study aimed to explore the effect of 1,25-dihydroxy vitamin D3 (1,25(OH)2D3) on the expression of interleukin-17 and -21 in asthma by establishing an asthma mice model.

ABSTRACT

Objective: To explore the effect of 1,25-dihydroxy vitamin D3 (1,25(OH)2D3) on the expression of interleukin (IL)-17 and IL-21 in asthma by establishing an asthma mice model.

Accepted: 
March 25, 2015
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