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Grenada

Meningo-encephalo-myelitis in Children during the Zika Virus Epidemic in Grenada

Issue: 
DOI: 
10.7727/wimjopen.2017.227
Pages: 
43–6
Synopsis: 
Zika Virus is neurotropic. We report two children from the Caribbean Island of Grenada, a three-year-old with acute neuro-inflammation who had intractable seizures, meningo-encephalitis, CSF pleocytosis and Zika IgM positive acute serology and a four-year-old with acute demyelinating encephalomyelitis manifesting as generalized seizures, optic neuritis, diffuse cerebral dysfunction, encephalopathy, impaired speech and ataxia who also had CSF pleocytosis as well as Zika IgM and Dengue IgM positive acute serologies. Both cases occurred during the 2016 Zika and Dengue fever epidemic in Grenada. Both children recovered completely. The aetiologic role of the Zika and Dengue arboviruses is discussed.

Zika Virus is neurotropic. We report two children from the Caribbean Island of Grenada, a three-year-old with acute neuro-inflammation who had intractable seizures, meningo-enceph-alitis, cerebrospinal fluid (CSF) pleocytosis and Zika Immunoglobulin M (IgM) positive acute serology and a four-year-old with acute demyelinating encephalomyelitis manifesting as generalized seizures, optic neuritis, diffuse cerebral dysfunction, encephalopathy, impaired speech and ataxia who also had CSF pleocytosis as well as Zika IgM and Dengue IgM positive acute serologies.

Accepted: 
December 18, 2017
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Characterization of Neuropathic Pain in Sickle Cell Disease

Issue: 
DOI: 
10.7727/wimjopen.2017.164
Pages: 
17-23
Synopsis: 
This study sought to identify the amount of nociceptive, affective and neuropathic pain components in sickle cell disease (SCD) in Grenada, West Indies. Characterization of pain in SCD will contribute to increased awareness and promote the development of adequate and effective pain management guidelines.

ABSTRACT

Accepted: 
October 9, 2017
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