B Jacobson

An Assessment of the Accuracy of Creatinine Measurements in Guyana

Issue:

Vol 69, Issue 1: 2021

DOI:

10.7727/wimj.2015.518

Pages:

4-8

Synopsis:

The accuracy of creatinine measurements in 16 Guyanese medical laboratories was assessed using blinded creatinine reference specimens. Creatinine methods in use in Guyana demonstrated imprecision and bias such that routine reporting of estimated glomerular filtration rates cannot be recommended at this time.

ABSTRACT

Background: The incidence of chronic kidney disease (CKD) is relatively high in Guyana. Estimated glomerular filtration rate (eGFR) reporting allows for early-stage CKD identification when therapeutic interventions can prevent CKD progression. Accurate creatinine measurements are essential for valid eGFR calculations.

Received:

13 Oct, 2015

Accepted:

26 Oct, 2015

Published:

30 Apr, 2021

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