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An Assessment of the Accuracy of Creatinine Measurements in Guyana

DOI: 
10.7727/wimj.2015.518
Pages: 
Synopsis: 
Accuracy of creatinine measurements in sixteen Guyanese medical laboratories was assessed using blinded creatinine reference specimens. Creatinine methods in use in Guyana demonstrated imprecision and bias such that routine reporting of eGFR cannot be recommended at this time,

ABSTRACT

Background: The incidence of chronic kidney disease (CKD) is relatively high in Guyana.  eGFR (estimated glomerular filtration rate) reporting allows for early-stage CKD identification, when therapeutic interventions can prevent CKD progression.  Accurate creatinine measurements are essential for valid eGFR calculations.  This study was undertaken to assess the accuracy of creatinine measurements in Guyana prior to implementing routine eGFR reporting.

Accepted: 
26 Oct, 2017
PDF Attachment: 
Journal Sections: 
e-Published: 10 Jul, 2017

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

An Assessment of the Accuracy of Creatinine Measurements in Guyana

DOI: 
10.7727/wimj.2015.518
Synopsis: 
The accuracy of creatinine measurements in sixteen Guyanese medical laboratories was assessed using blinded creatinine reference specimens. Creatinine methods in use in Guyana demonstrated imprecision and bias such that routine reporting of estimated glomerular filtration rate (eGFR) cannot be recommended at this time.

ABSTRACT

Background: The incidence of chronic kidney disease (CKD) is relatively high in Guyana. Estimated glomerular filtration rate (eGFR) reporting allows for early-stage CKD identification, when therapeutic interventions can prevent CKD progression.  Accurate creatinine measurements are essential for valid eGFR calculations. This study was undertaken to assess the accuracy of creatinine measurements in Guyana prior to implementing routine eGFR reporting.

Accepted: 
26 Oct, 2015
PDF Attachment: 
Journal Sections: 
e-Published: 01 Jun, 2017

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

What Are the Factors Affecting on the Mortality of COPD Patients in the ICU?

DOI: 
10.7727/wimj.2016.593
Synopsis: 
Morbidity and mortality rates of COPD are continuously increasing throughout the world. We aimed to determine factors associated with in-hospital-mortality of all causes following critical care admissions of patients with COPD. Features during admission to the ICU of patients were studied such as demographic and clinical features, laboratory analyses and comorbid diseases. Co-morbid diseases such as CHF, AF and postoperative care affect mortality the most in COPD patients who are hospitalized in ICU. Laboratory tests like creatinine and clinical features like being intubated upon admission, duration of mechanical ventilation and EF are other independent variables that affect mortality.

ABSTRACT

Background: Morbidity and mortality rates of Chronic obstructive pulmonary disease (COPD) are continuously increasing throughout the world. It is a major cause of death, imposes a great socioeconomic burden and constitutes a significant part of ICU patients.

Aim: To determine factors associated with in-hospital-mortality of all causes following   critical care admissions of patients with COPD.

Accepted: 
30 Mar, 2017
PDF Attachment: 
Journal Sections: 
e-Published: 27 Apr, 2017

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Global Registry of Acute Coronary Events (GRACE) Risk Score as a Predictor of In-hospital Mortality for Acute Coronary Syndrome in Trinidad and Tobago

Issue: 
DOI: 
10.7727/wimj.2014.172
Pages: 
52–9
Synopsis: 
The GRACE risk score, which was developed in a predominantly Caucasian population, was not previously tested in a Caribbean population. This study found it to be a reliable predictor of in-hospital mortality in a multi-ethnic Trinidadian acute coronary syndrome population, making it a useful risk stratification tool.

ABSTRACT

Objective: To determine whether risk stratification using the Global Registry of Acute Coronary Events (GRACE) risk score is a predictor of in-hospital mortality for ACS patients in a multi-ethnic Caribbean population.

Accepted: 
30 Sep, 2014
PDF Attachment: 
Journal Sections: 
e-Published: 12 May, 2015

Predicting 24-hour Urinary Protein Excretion in Afro-Caribbean Barbadians by Comparing Urine Protein Excretion over Different Durations versus Spot Collection

Issue: 
DOI: 
10.7727/wimj.2012.239
Pages: 
190–4
Synopsis: 
This article highlights the investigation of appropriate means of predicting 24-hour urinary protein excretion in Afro-Caribbeans in Barbados by assessing the correlation of urinary protein excretion between actual and measured protein excretion in a 24-hour urine collection, 12-hour (am and pm) and spot (am and pm) urine collections.

ABSTRACT

Accepted: 
14 Feb, 2012
PDF Attachment: 
Journal Sections: 
e-Published: 26 Jun, 2013

Predicting 24-hour Urinary Sodium Excretion in Afro-Caribbean Barbadians by Comparing Urine Sodium Excretion over Different Durations versus Spot Collection

Issue: 
DOI: 
10.7727/wimj.2012.240
Pages: 
181–5
Synopsis: 
This article highlights the investigation of appropriate means of predicting 24-hour urinary sodium excretion in Afro-Caribbeans in Barbados by assessing the correlation of urinary sodium excretion between actual and measured sodium excretion in a 24-hour urine collection, 12-hour (am and pm) and spot (am and pm) urine collections.

                                                                               ABSTRACT

Accepted: 
27 Feb, 2013
PDF Attachment: 
Journal Sections: 
e-Published: 26 Jun, 2013
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