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D Fernandes

Simvastatin Protects Osteoblasts from the Deleterious Effects of the Liquid Milieu of Multiple Myeloma

Issue: 
DOI: 
10.7727/wimj.2014.227
Pages: 
263–5
Synopsis: 
The microenvironment of multiple myeloma (MM), composed of different cells, is influenced by the massive presence of neoplastic plasma cells. Osteoblastic suppression and osteoclast induction is one of the tumour stimuli. Simvastatin protects osteoblasts from the deleterious effects of the liquid milieu of MM.

 ABSTRACT

Accepted: 
29 Oct, 2014
PDF Attachment: 
Journal Sections: 
e-Published: 02 Apr, 2015
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