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GM Favero

Diabetic Hyperglycaemia Protects Smooth Muscle Arterial Cells but Not Macrophages and Endothelial Cells from the Cytotoxic Effects of 7-Ketocholesterol: An In Vitro Study

Issue: 
DOI: 
10.7727/wimj.2016.499
Pages: 
483-7
Synopsis: 
In the study reported, macrophages, smooth muscle and endothelial arterial cells were challenged against different concentrations of 7-ketocholesterol in normoglycemic and high glucose conditions. The hyperglycaemic medium protects only smooth muscle artery cells against the cytotoxic effects of 7-ketocholesterol.

ABSTRACT

Accepted: 
18 Dec, 2017
PDF Attachment: 
Journal Sections: 
e-Published: 23 Jan, 2018

Simvastatin Protects Osteoblasts from the Deleterious Effects of the Liquid Milieu of Multiple Myeloma

Issue: 
DOI: 
10.7727/wimj.2014.227
Pages: 
263–5
Synopsis: 
The microenvironment of multiple myeloma (MM), composed of different cells, is influenced by the massive presence of neoplastic plasma cells. Osteoblastic suppression and osteoclast induction is one of the tumour stimuli. Simvastatin protects osteoblasts from the deleterious effects of the liquid milieu of MM.

 ABSTRACT

Accepted: 
29 Oct, 2014
PDF Attachment: 
Journal Sections: 
e-Published: 02 Apr, 2015
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