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N Afza

Lipoxygenase Inhibitory Tetraketones: Potential Remedial Source for Inflammation and Asthma

Issue: 
Pages: 
92–8
Synopsis: 
Twenty-one tetraketones were synthesized in high yields by condensation of cyclohexane-1, 3-dione with a variety of aldehydes in the presence of tetraethyl ammonium bromide (Et4N+Br¯) as catalyst under mild reaction conditions. Most of these compounds showed significant inhibitory activity against the enzyme lipoxygenase.

ABSTRACT

Objective: A series of tetraketones has been synthesized by way of a one pot synthesis and screened for inhibitory activity against the enzyme lipoxygenase.

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e-Published: 17 Sep, 2013

Natamycin Treatment of Experimental Candida albicans induced Keratomycosis in Rabbits

Issue: 
Pages: 
526–9
Synopsis: 
Natamycin has a significant effect against candida albicans in treating experimental keratomycosis.

ABSTRACT

Objective: The efficacy of topical natamycin 5% was studied using a reproducible model of keratomycosis
produced by Candida albicans in the rabbits.

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e-Published: 04 Jul, 2013
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