Twenty-one tetraketones were synthesized in high yields by condensation of cyclohexane-1, 3-dione with a variety of aldehydes in the presence of tetraethyl ammonium bromide (Et4N+Br¯) as catalyst under mild reaction conditions. Most of these compounds showed significant inhibitory activity against the enzyme lipoxygenase.

Natamycin has a significant effect against candida albicans in treating experimental keratomycosis.