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Beta Cell Regenerating Potential of Azadirachta indica (Neem) Extract in Diabetic Rats

Issue: 
DOI: 
10.7727/wimj.2014.224
Pages: 
13–17
Synopsis: 
Neem leaf extract improved β cell regeneration but did not reduce blood glucose in diabetic rats.

ABSTRACT

Objective: This study evaluated the ability of 0.8% neem leaf extract (NLE) to treat diabetes mellitus by assessing its effects on blood glucose, insulin levels and islet morphology in streptozotocin (STZ)-induced diabetic Sprague-Dawley rats.

Accepted: 
31 Oct, 2014
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e-Published: 05 May, 2015

The Emergence of Qnr-Mediated Quinolone Resistance among Enterobacteriaceae in Jamaica

Issue: 
Pages: 
241–4
Synopsis: 
There is identified qnr-mediated quinolone resistance and qnr co-determinants among enterobacteriaceae isolates in Jamaica.

ABSTRACT

Objective: Quinolone resistance is usually caused by various chromosomal mutations, but has been more recently associated with plasmids which carry the qnr determinant. The aim of this study is to investigate the prevalence of qnr genes in clinical isolates of Enterobacteriaceae in Jamaica.

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e-Published: 07 Oct, 2013

Comparison of Antibiotic Resistance and Virulence Factors in Pigmented and Non-pigmented Pseudomonas aeruginosa

Issue: 
Pages: 
24–32
Synopsis: 
The study found that pigment production was significantly associated with multi-drug resistance, presence of virulence-associated genes, and expression of some important virulence factors. The authors conclude that since pigment production is easy to determine, this might be a good starting point to identify the virulence status of an isolate.

ABSTRACT

Objective: Pseudomonas aeruginosa produces multiple virulence factors that have been implicated in pathogenesis and quorum sensing. The aim of this study was to determine differences in the virulence factors of pigmented and non-pigmented P aeruginosa isolates.

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e-Published: 17 Oct, 2013
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