Acanthosis nigricans (AN) is a cutaneous disorder associated with various diseases. There are few documented cases of regression of AN. We discuss a case of a 48-year old diabetic woman with resolution of AN after treatment with sitagliptin and pioglitazone.
This manuscript has been assigned to a volume and issue but has not yet been published. It is either being edited, typeset or is in the proof stage of publication.
In the pre-published stage, this manuscript may contain statements, opinions, and information that have errors in facts, figures, or interpretation. Any final changes in this manuscript will be made at the time of publication and will be reflected in the final electronic version of the issue. The editors and authors and their respective employees are not responsible or liable for the use of any such inaccurate or misleading data, opinion or information contained in the articles in this section.
This manuscript has been assigned to a volume and issue but has not yet been published. It is either being edited, typeset or is in the proof stage of publication.
In the pre-published stage, this manuscript may contain statements, opinions, and information that have errors in facts, figures, or interpretation. Any final changes in this manuscript will be made at the time of publication and will be reflected in the final electronic version of the issue. The editors and authors and their respective employees are not responsible or liable for the use of any such inaccurate or misleading data, opinion or information contained in the articles in this section.
Environmental factors may be of paramount importance as driving forces in the changing trend.
ABSTRACT
The incidence of Type I diabetes mellitus in children has increased worldwide over the past 50 years. This increase has occurred in rich and poor countries in Europe, Asia, the Americas and Oceania. Rapid increases in incidence in genetically stable populations eg Finland and Sardinia imply that environmental factors are of paramount importance as driving forces in this changing trend. The significance of these trends and putative aetiological factors are reviewed.
Graves’ ophthalmopathy occurs in 25% – 50% of patients with Graves’ Hyperthyroidism. Euthyroid Graves’ ophthalmopathy is much less common, occurring in approximately 10% of patients with Graves’ ophthalmopathy (1). Review of the literature revealed no reports of euthyroid Graves’ ophthalmopathy in children. The case of an eight-year old female with euthyroid Graves’ ophthalmopathy is reported.
This manuscript has been assigned to a volume and issue but has not yet been published. It is either being edited, typeset or is in the proof stage of publication.
In the pre-published stage, this manuscript may contain statements, opinions, and information that have errors in facts, figures, or interpretation. Any final changes in this manuscript will be made at the time of publication and will be reflected in the final electronic version of the issue. The editors and authors and their respective employees are not responsible or liable for the use of any such inaccurate or misleading data, opinion or information contained in the articles in this section.
The frequency of 21-hydroxylase deficiency in The Bahamas is one of
the highest in the world.
ABSTRACT
Objective: To determine the frequency of 21-hydroxylase deficiency in The Bahamas and the spectrum of this disorder.
Methods: Patients referred for evaluation of virilization, precocious puberty, ambiguous genitalia and salt wasting had blood taken for 17-hydroxyprogesterone (17-OH progesterone) which was measured by Enzyme-Linked Immunosorbent Assay (ELISA).