Close Menu

SX Zhang

The Application of Chromosome Abnormality Chip Detection in Male Infertility

Issue: 
DOI: 
10.7727/wimj.2013.213
Synopsis: 
Chromosome abnormality chip detection system provides a sensitive, economic and high-throughput method for detecting the deletion or amplification of genomic DNA sequences of infertile patients.

ABSTRACT

Objective: To discuss the application of microarray technology in the diagnosis of male infertility.

Methods: Sixteen loci, including a sex-determining region on the Y chromosome, were investigated by polymerase chain reaction (PCR) in infertile male patients. Chromosome abnormality chip with 180 000 probes was used to detect small deletion, small amplification and loss of heterozygosity.

Accepted: 
20 Aug, 2013
PDF Attachment: 
Journal Sections: 
e-Published: 02 Apr, 2014

Pre-published Manuscript

This manuscript has been assigned to a volume and issue but has not yet been published. It is either being edited, typeset or is in the proof stage of publication.
In the pre-published stage, this manuscript may contain statements, opinions, and information that have errors in facts, figures, or interpretation. Any final changes in this manuscript will be made at the time of publication and will be reflected in the final electronic version of the issue. The editors and authors and their respective employees are not responsible or liable for the use of any such inaccurate or misleading data, opinion or information contained in the articles in this section.

Subscribe to RSS - SX Zhang
Top of Page