Close Menu

Gonadotropin-releasing hormone agonist

Short-term Administration of Gonadotropin-releasing Hormone Agonist (Buserelin) Induces Apoptosis in Rat Ovarian Developmental Follicles

Issue: 
DOI: 
10.7727/wimj.2016.170
Pages: 
319-25
Synopsis: 
The short-term administration of high dose buserelin decreases the number of follicles in mature rat ovaries and has an inhibitory effect on follicular development. Also, the buserelin increases apoptosis in the granulosa cells and serum estradiol (E2) level, but the serum progesterone levels decrease.

ABSTRACT

Objective: To investigate the effects of buserelin on the development of follicles, apoptosis index and steroid hormones level.

Accepted: 
15 Jun, 2016
PDF Attachment: 
Journal Sections: 
e-Published: 30 Jun, 2016
Subscribe to RSS - Gonadotropin-releasing hormone agonist
Top of Page