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Effect of Hydro-alcoholic Extract from Prosopis Farcta Leaves on Liver Injury Caused by High-fat Diet in Rats

Issue: 
DOI: 
10.7727/wimj.2016.507
Pages: 
13-9
Synopsis: 
The hydro-alcoholic extract of the leaves of Prosopis farcta was evaluated for hepatoprotective and antioxidant activities in rats submitted to a high-fat diet. Oral administration of extract of Prosopis farcta leaves resulted in significant amelioration of the altered indices.

ABSTRACT

Objective: To determine the hepatoprotective and antioxidant effects of hydro-alcoholic extract of Prosopis farcta (P farcta) leaves on high fat diet-fed (HFDF) rats.

Revised: 
13 Jun, 2017
Accepted: 
13 Nov, 2017
PDF Attachment: 
Journal Sections: 
Journal Authors: 
e-Published: 15 Nov, 2017

Immunohistopathological and Biochemical Study of the Effects of Dead Nettle (Urtica Dioica) Extract on Preventing Liver Lesions Induced by Experimental Aflatoxicosis in Rats

Issue: 
DOI: 
10.7727/wimj.2016.126
Pages: 
254-61
Synopsis: 
This paper studied the preventive effects of dead nettle extract on liver lesions that were induced by experimental aflatoxicosis in rats. According to the biochemical and histopathological findings of the study, antioxidant system activity increased and lipid peroxidation and liver enzyme levels decreased in the group that received dead nettle leaf extract. As a result, it could be concluded that dead nettle leaf extract had hepatoprotective effects against aflatoxicosis.

ABSTRACT

Objective: Aflatoxicosis is a mycotoxicosis infection with an acute or chronic course that forms due to aflatoxins (AFs) in humans and animals. Aflatoxins primarily affect the liver and can lead to histopathological necrosis, fibrosis and hepatocarcinogenesis of the organ. This paper studied the preventive effects of dead nettle leaf (Urtica dioica leaf; UDL) extract on liver lesions that were induced by experimental aflatoxicosis in rats.

Accepted: 
25 May, 2016
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Journal Sections: 
Journal Authors: 
e-Published: 13 Jul, 2016

The Effects on Offsprings of Diabetes Mellitus Induced by Different Chemical Agents in Pregnant Rats with Advanced Pregnancy

DOI: 
10.7727/wimj.2015.587
Synopsis: 
Diabetes is the most important cause of perinatal mortality, and a four to eight-fold greater malformation rate is observed among babies of diabetic mothers than among the general population. Cardiac anomalies and central nervous system anomalies are the most common anomalies observed in babies of diabetic mothers.

ABSTRACT

Accepted: 
07 Dec, 2015
PDF Attachment: 
Journal Sections: 
Journal Authors: 
e-Published: 30 Mar, 2016

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Effect of Yi Fu Kang Oral Liquid on Gastrointestinal Side Effects Caused by Chemotherapy

DOI: 
10.7727/wimj.2015.076
Synopsis: 
Yi Fu Kang oral liquid can enhance the function of the gastrointestinal tract of animals by reducing the number of emetic responses, protecting the gastric mucosa and propelling movement of small intestine contents.

ABSTRACT

Objective: We aimed to investigate whether Yi Fu Kang oral liquid (YFK) could reduce the gastrointestinal side effects caused by chemotherapy.

Accepted: 
26 Mar, 2015
PDF Attachment: 
Journal Sections: 
e-Published: 23 Oct, 2015

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Different Doses and Routes of Administration of Methimazole Affect Thyroid Status in Methimazole-induced Hypothyroidism in Rats

Issue: 
DOI: 
10.7727/wimj.2014.241
Pages: 
93–7
Synopsis: 
In the present study, we established and compared differences of the rat’s hypothyroid model induced by MMI added to drinking water or given through an intragastric tube.

ABSTRACT

Objective: It is agreed that methimazole (MMI) can be administered to induce hypothyroidism. However, there are conflicting data about its effect on thyroid function and development in rats through different administrations. In the present study, we established and compared differences of the rat hypothyroid model induced by MMI added to drinking water or given through an intragastric tube.

Accepted: 
31 Oct, 2014
PDF Attachment: 
Journal Sections: 
e-Published: 07 May, 2015

The Effect of Borax on Hematological Parameters and Immunoglobulin Values in Rats

DOI: 
10.7727/wimj.2016.359
Synopsis: 
Boron supplementation in animal and human nutrition may have important effects on various metabolic, physiological systems of the organism. The aim of this study was to evaluate the effect of borax on hematological parameters and immunoglobulin values in the rats.

ABSTRACT

Objective: Boron is an essential metalloid which plays a key role in plants and animals metabolisms. In the last few years boron compounds became increasingly more frequent in some hematological diseases. The aim of this study was to evaluate the effect of borax as a boron source on hematological parameters and immunoglobulin (Ig) values in the rats.

Accepted: 
12 Aug, 2016
PDF Attachment: 
Journal Sections: 
e-Published: 12 Aug, 2016

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Short-term Administration of Gonadotropin-releasing Hormone Agonist (Buserelin) Induces Apoptosis in Rat Ovarian Developmental Follicles

DOI: 
10.7727/wimj.2016.170
Synopsis: 
The short-term administration of high dose buserelin decreases the number of follicles in mature rat ovaries and has an inhibitory effect on follicular development. Also, the buserelin increases apoptosis in the granulosa cells and serum estradiol (E2) level, whereas serum progesterone levels decreased.

ABSTRACT

Objective: The aim of the present study was to investigate the effects of buserelin on the development of follicles, apoptosis index, and steroid hormones level.

Accepted: 
15 Jun, 2016
PDF Attachment: 
Journal Sections: 
e-Published: 30 Jun, 2016

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Histopathological Changes That Occur on the Testicular and Penile Tissues Depending on the Treatment of Human Chorionic Gonadotropin: Rat Model

DOI: 
10.7727/wimj.2015.282
Synopsis: 
hCG treatment may lead to the deterioration in testicular histology and the histological changes in the penile tissue. The degradation in the testicular tissue and these changes formed in the penile tissue may affect the erectile tissue function.

ABSTRACT

Objectives: To examine the histopathological effects of human chorionic gonadotropin (hCG) treatment on the penile and the testicular tissue in rat model.

Accepted: 
11 Sep, 2015
PDF Attachment: 
Journal Sections: 
e-Published: 22 Mar, 2016

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

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