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Y Rasmi

Expression of Genes Encoding Kinin B1 and B2 Receptors in Pripheral Blood Mononuclear Cells (PBMC) from Patient with Slow Coronary Flow

DOI: 
10.7727/wimj.2017.006
Synopsis: 
This study investigated the gene expression of B1R and B2R in PBMC from patients with slow coronary flow (SCF). It can be concluded that B1R signaling pathway may provide a structural basis of the important role of kinins in SCF pathogenesis.

ABSTRACT

Objective: Slow coronary flow (SCF) is specified by the delayed passage of contrast in the absence of obstructive epicardial coronary disease. Its etiopathology remains unclear. Kinins are mediators of vasodilatation as well as inflammation in human body. This study aimed to investigate the gene expression of kinins B1 and B2 receptors (B1R and B2R) in peripheral blood mononuclear cells (PBMC) from patients with SCF.

Accepted: 
12 May, 2017
PDF Attachment: 
Journal Sections: 
e-Published: 17 May, 2017

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Short-term Administration of Gonadotropin-releasing Hormone Agonist (Buserelin) Induces Apoptosis in Rat Ovarian Developmental Follicles

DOI: 
10.7727/wimj.2016.170
Synopsis: 
The short-term administration of high dose buserelin decreases the number of follicles in mature rat ovaries and has an inhibitory effect on follicular development. Also, the buserelin increases apoptosis in the granulosa cells and serum estradiol (E2) level, whereas serum progesterone levels decreased.

ABSTRACT

Objective: The aim of the present study was to investigate the effects of buserelin on the development of follicles, apoptosis index, and steroid hormones level.

Accepted: 
15 Jun, 2016
PDF Attachment: 
Journal Sections: 
e-Published: 30 Jun, 2016

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

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