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E-selectin may have an important function in Graves’ disease with leukopenia, and glucocorticoids (prednisone) could decrease E-selectin level; this may be a new therapy target for Graves’ disease with leukopenia.
Findings from this study suggest that impairment of reproductive function associated with thyroid dysfunction is in attendant with derangement of hormonal milieu and alteration in reproductive organs cytoarchitecture. Luteinizing hormone and oestradiol are implicated.
Background: It has been established that thyroid dysfunction causes impairment of reproductive function. However, laboratory and human studies that associated this with female reproductive hormones are conflicting and data reporting the effects of thyroid dysfunction on reproductive organs are insufficient.
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West Indian Medical Journal
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