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H Jiang

De novo CD5-positive Diffuse Large B-cell Lymphoma Primarily Presenting as Spinal Cord Compression: A Case Report

Issue: 
DOI: 
10.7727/wimjopen.2015.009
Pages: 
106–8

ABSTRACT

De novo CD5-positive (CD5+) diffuse large B-cell lymphoma (DLBCL) is a highly aggressive subtype of DLBCL with a high incidence of misdiagnosis when spinal cord compression is the initial symptom. We report a case of a 45-year old man with de novo CD5+ DLBCL primarily presenting as spinal cord compression. Unfortunately, this patient was resistant to rituximab-based therapy, which indicated a poor prognosis.

Accepted: 
February 5, 2015
PDF Attachment: 
Journal Sections: 

YY1-miR-146a-YY1 Regulatory Circuitry: A Potential Mechanism of Prostate Cancer Formation and Progression

Issue: 
DOI: 
10.7727/wimjopen.2013.314
Synopsis: 
YY1, a critical regulator in prostate cancer, is predicted to be a direct target of miR-146a and binds to promoter region of miR-146a which demonstrates that YY1-miR-146a-YY1 regulatory circuitry may contribute to prostate cancer and serve as a future intervention target.

ABSTRACT

Accepted: 
January 20, 2014
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Journal Sections: 
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