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D Bayram

The Efficacy of H89 on Aquaporin 5 levels in Asthmatic Rat Models

DOI: 
10.7727.wimj/2016.313
Synopsis: 
Asthma is a disease that progresses depending on the increased sensitivity in the respiratory tract and hypersecretion by goblet cells in bronchia. Inflammation sources that play a role in asthma’s physiopathology are T lymphocytes, mast cells, eosinophils, and macrophages. Biopsy studies have revealed that there are correlations between density of inflammation and intensity of the diseases The effect of specific protein kinase A inhibitor H89 treatment reduced Aq 5 receptor expressions on the lung tissue.

ABSTRACT

Objective: The effect of specific protein kinase A inhibitor H89 on Aquaporin 5 levels, which has a role in the inflammation of asthma pathogenesis, was investigated in this study.

Accepted: 
16 Aug, 2016
PDF Attachment: 
Journal Sections: 
e-Published: 22 Aug, 2016

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