M Saygin

The Efficacy of H89 on Aquaporin 5 Levels in Asthmatic Rat Models

Issue:

Vol 71, Issue 1: 2024

DOI:

10.7727.wimj/2016.313

Pages:

37-41

Synopsis:

Asthma is a disease that progresses depending on the increased sensitivity in the respiratory tract and hypersecretion by goblet cells in bronchia. Inflammation sources that play a role in asthma’s physiopathology are T lymphocytes, mast cells, eosinophils, and macrophages. Biopsy studies have revealed that there are correlations between density of inflammation and intensity of the diseases The effect of specific protein kinase A inhibitor H89 treatment reduced Aq 5 receptor expressions on the lung tissue.

ABSTRACT

Background: The effect of a specific protein kinase A inhibitor H89 on Aquaporin 5 (AQ5) levels, which has a role in the inflammation of asthma pathogenesis, was investigated in this study.

Objective: To prove that H89, which was thought to be a promising agent, may show antiinflammatory activity in the treatment of asthma by causing inhibition of the protein kinase A enzyme that is involved in inflammation.

Received:

27 Jun, 2016

Accepted:

16 Aug, 2016

Published:

30 Mar, 2024

PDF Attachment:

wimj-iss1-2024_37_41.pdf

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e-Published: 22 Aug, 2016

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Impact of L-carnitine and Selenium Treatment on Testicular Apoptosis in Rats Exposed to 2.45 GHz Microwave Energy

Issue:

Vol 64, Issue 2: March (2015)

DOI:

10.7727/wimj.2014.205

Pages:

55–61

Synopsis:

Electromagnetic radiation by wireless device (2.45 GHz) induces testicular apoptosis. Effects of supplemental selenium and L-carnitine on testicular apoptosis by 2.45 GHz microwave energy were evaluated.

ABSTRACT

Objective: It has been suggested that electromagnetic radiation (EMR) by wireless devices (2.45 GHz) induces testicular apoptosis. We investigated if supplemental selenium (Se) and L-carnitine may reduce this adverse effect.

Received:

27 Aug, 2014

Accepted:

29 Oct, 2014

PDF Attachment:

wimjmar2015_55_61.pdf

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e-Published: 13 Apr, 2015

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Effects of Ionizing Radiation on Respiratory Function Tests and Blood Parameters in Radiology Staff

Issue:

Vol 63, Issue 1: Jan (2014)

DOI:

10.7727/wimj.2012.311

Pages:

40–5

Synopsis:

Radiology staff constantly exposed to ionizing radiation was evaluated to determine the relationship between pulmonary function and blood parameters. Although the respiratory functions of radiology staff are affected by many factors, continuous exposure to ionizing radiation is one of the important parameters. Radiology staff should be informed about preventable factors that negatively affect respiratory functions.

ABSTRACT

Aim: To evaluate pulmonary function tests and blood parameters and their relationship with sociodemographic data for radiology staff continuously exposed to ionizing radiation.

Received:

05 Dec, 2012

Accepted:

12 Feb, 2013

Journal Sections:

Keywords:

respiratory function tests

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