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E Karataslioglu

Thymoquinone Reduces Oxidative and Nitrosative Stress in Tongue Tissue of Rats Exposed to Total Cranial Irradiation

Issue: 
DOI: 
10.7727/wimj.2015.297
Pages: 
543-50
Synopsis: 
This is the first study that investigates the effect of thymoquinone on the oxidant/antioxidant system in the irradiated tongue tissue of the rats.

ABSTRACT

Background: Head and neck cancer patients treated with radiotherapy suffer severe side effects during and following their treatment. Efforts to decrease toxicity of irradiation to normal tissue, organs and cells have led to searching for cytoprotective agent. Investigations for effective and non-toxic compounds with radioprotective capability led to increasing interest in antioxidant such as Thymoquinone (TQ).

Accepted: 
12 Jun, 2015
PDF Attachment: 
Journal Sections: 
e-Published: 22 Mar, 2016
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