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F Hussain

Antidiabetic Potential of Onosma hispidum Roots

DOI: 
10.7727/wimj.2016.436
Synopsis: 
In present study, antidiabetic potential of Onosma hispidum roots were assessed in diabetic animal models. O hispidum roots exhibited antihyperglycemic and antihyperlipidemic effects. In addition, histopathological investigation revealed pancreatic beta cells regeneration activity by plant roots.

ABSTRACT

Objective: To investigate the antihyperglycemic, antihyperlipidemic and pancreatic beta cells regeneration potentials of Onosma hispidum (ratanjot) root extracts in alloxan-induced diabetic rabbits.

Accepted: 
13 Feb, 2017
PDF Attachment: 
Journal Sections: 
Journal Authors: 
e-Published: 02 Mar, 2017

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Manuscripts that are “Published at Acceptance” have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear prior to being copy edited or formatted in the style guide of this Journal. The contents of the manuscript may change before it is published in its final form. While accepted manuscripts are not yet assigned a volume, issue, or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. Manuscripts in this section will be removed once they have been assigned to a volume and issue, but will still retain the DOI and date of e-publication.

Antidiabetic Evaluation of Momordica charantia L Fruit Extracts

Issue: 
DOI: 
10.7727/wimj.2013.180
Pages: 
294–9
Synopsis: 
Antidiabetic activities (hypoglycaemic, hypolipidaemic and pancreatic beta cells regeneration) of Momordica charantia (MC) fruits were investigated in alloxan diabetic rabbits. Although MC extracts showed significant hypoglycaemic effects (p < 0.05), these did not result in normal glucose and lipid profile levels. Regeneration of pancreatic beta cells by MC extracts was minimal, with fractional improvement produced by glibenclamide.

ABSTRACT

Accepted: 
29 Oct, 2013
PDF Attachment: 
Journal Sections: 
Journal Authors: 
e-Published: 08 May, 2014
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