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Association between Mannose-Binding Lectin 2 Gene Polymorphism and Liver Fibrosis in Patients with Chronic Viral Hepatitis

DOI: 
10.7727/wimj.2016.155
Synopsis: 
MBL2 Gene Polymorphism were investigated in patients with viral Hepatitis B and C. No significant differences in allele frequencies for any polymorphism were observed between patients and controls.

ABSTRACT

Objective: Mannose-Binding Lectin (MBL) has become a popular molecule in investigations on basic and clinical Gastroenterology and contributed to new approaches to the understanding of infectious and immune diseases associated with intestine and liver. The aim of the present study was to investigate the association between codon 54 polymorphisms in MBL2 gene coding MBL and predisposition to fibrosis in patients with viral Hepatitis B and C.

Accepted: 
25 May, 2016
PDF Attachment: 
Journal Sections: 
e-Published: 14 Jul, 2016

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Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

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