In this study, Mannose-Binding Lectin 2 (MBL2) gene polymorphism were investigated in patients with viral Hepatitis B and C. No significant differences in allele frequencies for any polymorphism were observed between patients and controls.
ABSTRACT
Objective: Mannose-binding lectin (MBL) has become a popular molecule in investigations on basic and clinical gastroenterology and contributed to new approaches to the understanding of infectious and immune diseases associated with intestine and liver. The aim of the present study was to investigate the association between codon 54 polymorphisms in MBL2 gene coding MBL and predisposition to fibrosis in patients with viral hepatitis B and C.
The present study was designed to evaluate the relationship between HBV infection and type 2 diabetes mellitus first time from Pakistan and found that HBV infection did not enhance the risk of diabetes despite the significant differences in the biochemical parameters among the study's sample.
ABSTRACT
Background: Hepatitis B virus (HBV) infection and diabetes mellitus are major health problems associated with significant morbidity and mortality. The published literature suggests an association of diabetes mellitus with liver disease. However, the role of HBV infection in diabetes aetiology is still controversial. The present study was conducted to explore the veracity of this enigmatic association among Pakistani subjects.