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M Tarakcioglu

Propolis and Caffeic Acid Phenethyl Ester Attenuates Nitrosative Stress in Lens Tissue in Radiation-induced Cataracts in Rats

Issue: 
DOI: 
10.7727/wimj.2015.445
Pages: 
362-7
Synopsis: 
The aim of this study was to investigate whether propolis and caffeic acid phenethyl ester (CAPE) prevent radiation-induced cataractogenesis. The results obtained in the study suggest that propolis and CAPE have free radical, scavenging activities in the irradiation-induced cataractogenesis.

 ABSTRACT

Objective: Eye morbidity is widely observed in patients receiving total body irradiation prior to bone marrow transplantation or radiotherapy for ocular or head and neck cancers. Cataract blindness is the major cause of preventable blindness worldwide, especially in the developing countries. The aim of this study was to investigate whether propolis and caffeic acid phenethyl ester (CAPE) prevent radiation-induced cataractogenesis.

Accepted: 
08 Sep, 2015
PDF Attachment: 
Journal Sections: 
e-Published: 04 Feb, 2016

The Radioprotective Effects of Caffeic Acid Phenethyl Ester and Thymoquinone on Oxidative and Nitrosative Stress in Liver Tissue of Rats Exposed to Total Head Irradiation

Issue: 
DOI: 
10.7727/wimj.2014.176
Pages: 
1–7
Synopsis: 
This study investigates the effects of the addition of caffeic acid phenethyl ester (CAPE) and thymoquinone on oxidative and nitrosative stress in the liver tissue of irradiated rats. Thymoquinone and CAPE decrease oxidative and nitrosative stress markers and have antioxidant effects, which also increase antioxidant capacity in the liver tissue of irradiated rats.

ABSTRACT

Objective: The aim of this study is to investigate the effects of addition of caffeic acid phenethyl ester (CAPE) and thymoquinone (TQ)on oxidative and nitrosative stress in the liver tissue of (IR) irradiated rats.

Methods: Forty Sprague-Dawley rats were divided into five groups to test the radioprotective effectiveness of TQand CAPE administered by intraperitoneal injection. Appropriate control groups were also studied.

Accepted: 
12 Aug, 2014
PDF Attachment: 
Journal Sections: 
e-Published: 12 May, 2015
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