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Caffeic acid phenethyl ester

Protective Effects of Caffeic Acid Phenethyl Ester on Isoniazid and Rifampicin-induced Hepatic and Pancreatic Injury

Issue: 
DOI: 
10.7727/wimj.2015.561
Pages: 
350-5
Synopsis: 
This study investigated the protective effects of caffeic acid phenethyl ester (CAPE) against rifampicin-isoniazid-induced hepatic and pancreatictoxicity in terms of histopathological deterioration, oxidative stress (paraoxonase-1, total antioxidant status, total oxidant status) and biochemical parameters changes. The side effects of isoniazid and rifampicin treatment on hepatic and pancreatic tissues may be prevented with CAPE.

ABSTRACT

Objective: To investigate the protective effects of caffeic acid phenethyl ester (CAPE) against isoniazid (INH)- and rifampicin (RFP)-induced hepatic and pancreatic damage.

Accepted: 
04 Jan, 2016
PDF Attachment: 
Journal Sections: 
e-Published: 30 Mar, 2016

Propolis and Caffeic Acid Phenethyl Ester Attenuates Nitrosative Stress in Lens Tissue in Radiation-induced Cataracts in Rats

Issue: 
DOI: 
10.7727/wimj.2015.445
Pages: 
362-7
Synopsis: 
The aim of this study was to investigate whether propolis and caffeic acid phenethyl ester (CAPE) prevent radiation-induced cataractogenesis. The results obtained in the study suggest that propolis and CAPE have free radical, scavenging activities in the irradiation-induced cataractogenesis.

 ABSTRACT

Objective: Eye morbidity is widely observed in patients receiving total body irradiation prior to bone marrow transplantation or radiotherapy for ocular or head and neck cancers. Cataract blindness is the major cause of preventable blindness worldwide, especially in the developing countries. The aim of this study was to investigate whether propolis and caffeic acid phenethyl ester (CAPE) prevent radiation-induced cataractogenesis.

Accepted: 
08 Sep, 2015
PDF Attachment: 
Journal Sections: 
e-Published: 04 Feb, 2016
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