MG Brown

Dengue HLA Associations in Jamaicans

Issue:

Vol 60, issue 2 (2011)

Pages:

126–31

Synopsis:

The HLA dengue associations in Jamaicans differ from those found in other ethnic populations. While HLA-A *24 and – DRβ5* 01/02 were associated with having dengue, HLA-A *23, -CW*04, -DQβ*02, DQβ*03 and –DQβ*06 were protective.

ABSTRACT

Background: Polymorphisms in the human leukocyte antigen (HLA) genes might predispose certain individuals to dengue fever (DF) and the severe forms of the disease: dengue haemorrhagic fever/ dengue shock syndrome (DHF/DSS).

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ms_m_brown3_wimj.qxd_.pdf

Journal Sections:

Keywords:

human leukocyte antigen

Journal Authors:

e-Published: 17 Oct, 2013

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Molecular Epidemiology of Dengue in Jamaica Dengue Virus Genotypes in Jamaica, 2007

Issue:

Vol 60, issue 2 (2011)

Pages:

120–5

Synopsis:

A study of dengue viruses that were in circulation in Jamaica in 2007 identified strains of DENV-1 genotype III, DENV-2 strains of the American, American-Asian and Asian genotypes while DENV-4 strains segregated into a separate clade from published reference sequences.

ABSTRACT

PDF Attachment:

ms_m_brown2_wimj.qxd_.pdf

Journal Sections:

Keywords:

phylogenetic sequencing

Journal Authors:

e-Published: 17 Oct, 2013

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Dengue Virus Serotypes in Jamaica, 2003−2007

Issue:

Vol 60, issue 2 (2011)

Pages:

114–9

Synopsis:

A study of the dengue viruses that were in circulation showed that all 4 serotypes were in circulation during 2003–2007 and the most prevalent were dengue serotypes 2 and 4.

ABSTRACT

Background: Dengue virus (DENV) infection is increasing in prevalence and severity globally. The severity of dengue is influenced by several factors including the immune response, viral and host genetic factors.

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ms_mg_brown1_wimj.qxd_.pdf

Journal Sections:

Keywords:

outbreak cell cultures

Journal Authors:

MG Brown

RA Salas