A study of the dengue viruses that were in circulation
showed that all 4 serotypes were in circulation during
2003–2007 and the most prevalent were dengue
serotypes 2 and 4.
Background: Dengue virus (DENV) infection is increasing in prevalence and severity globally. The severity of dengue is influenced by several factors including the immune response, viral and host genetic factors.
A study of dengue viruses that were in circulation in
Jamaica in 2007 identified strains of DENV-1 genotype
III, DENV-2 strains of the American, American-Asian
and Asian genotypes while DENV-4 strains segregated
into a separate clade from published reference
The HLA dengue associations in Jamaicans differ from
those found in other ethnic populations. While HLA-A
*24 and – DRβ5* 01/02 were associated with having
dengue, HLA-A *23, -CW*04, -DQβ*02, DQβ*03 and
–DQβ*06 were protective.
Background: Polymorphisms in the human leukocyte antigen (HLA) genes might predispose certain individuals to dengue fever (DF) and the severe forms of the disease: dengue haemorrhagic fever/ dengue shock syndrome (DHF/DSS).
Patients from two tertiary referral hospitals were assessed to determine whether Type 2 diabetes mellitus was present in Jamaican diabetic youth. Type 2 diabetes accounted for 22% of cases. Obesity was the most important clinical predictor of Type 2 diabetes.
Objectives: To assess the frequency of youth onset Type 2 diabetes mellitus (T2D) in Jamaica and the characteristics of youth with this form of diabetes.
The seroprevalences of hepatitis B virus (HBV), hepatitis C virus (HCV), human T lymphotropic virus type-1 (HTLV-1) and syphilis were determined in 129 HIV-1-infected patients using commercially prepared reagents. The seroprevalences were HCV, 0% (0/129); HBV, 37% (48/129); HTLV-1, 5% (6/129) and syphilis, 20% (26/129). Fifteen per cent (19/129) of the patients had active/chronic HBV infection.
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Some antibiotics, in addition to their antimicrobial effects, modify the host immune response. Cotrimoxazole unIike ciprofloxacin, ceftazidime, and piperacillintazobactam suppressed TNF alpha secretion from S maltophilia stimulated cells at therapeutic concentrations.
The majority of strains of HIV-1 isolated from HIV-1 infected individuals in Jamaica were found to be HIV- 1 subtype B. The less frequently found HIV-1 subtypes were C, D and E and some strains were untypable by the methods used.