Close Menu

Books in a Library

MF Smikle

Dengue HLA Associations in Jamaicans

Issue: 
Vol 60, issue 2 (2011)
Pages: 
126–31
Synopsis: 
The HLA dengue associations in Jamaicans differ from those found in other ethnic populations. While HLA-A *24 and – DRβ5* 01/02 were associated with having dengue, HLA-A *23, -CW*04, -DQβ*02, DQβ*03 and –DQβ*06 were protective.

ABSTRACT

Background: Polymorphisms in the human leukocyte antigen (HLA) genes might predispose certain individuals to dengue fever (DF) and the severe forms of the disease: dengue haemorrhagic fever/ dengue shock syndrome (DHF/DSS).

PDF Attachment: 
PDF icon ms_m_brown3_wimj.qxd_.pdf
Journal Sections: 
Original Articles
Keywords: 
Dengue Infection
Alleles
cohort
ethnicity
human leukocyte antigen
immune response
polymorphisms
Journal Authors: 
MG Brown
RA Salas
IE Vickers
OD Heslop
MF Smikle
e-Published: 17 Oct, 2013

Molecular Epidemiology of Dengue in Jamaica Dengue Virus Genotypes in Jamaica, 2007

Issue: 
Vol 60, issue 2 (2011)
Pages: 
120–5
Synopsis: 
A study of dengue viruses that were in circulation in Jamaica in 2007 identified strains of DENV-1 genotype III, DENV-2 strains of the American, American-Asian and Asian genotypes while DENV-4 strains segregated into a separate clade from published reference sequences.

ABSTRACT

PDF Attachment: 
PDF icon ms_m_brown2_wimj.qxd_.pdf
Journal Sections: 
Original Articles
Keywords: 
Caribbean
surveillance
clade
epidemic
genotypes
phylogenetic sequencing
strain
Journal Authors: 
MG Brown
RA Salas
IE Vickers
OD Heslop
MF Smikle
e-Published: 17 Oct, 2013

Dengue Virus Serotypes in Jamaica, 2003−2007

Issue: 
Vol 60, issue 2 (2011)
Pages: 
114–9
Synopsis: 
A study of the dengue viruses that were in circulation showed that all 4 serotypes were in circulation during 2003–2007 and the most prevalent were dengue serotypes 2 and 4.

ABSTRACT

Background: Dengue virus (DENV) infection is increasing in prevalence and severity globally. The severity of dengue is influenced by several factors including the immune response, viral and host genetic factors.

PDF Attachment: 
PDF icon ms_mg_brown1_wimj.qxd_.pdf
Journal Sections: 
Original Articles
Keywords: 
Jamaica
Dengue virus
immunity
outbreak cell cultures
Journal Authors: 
MG Brown
RA Salas
IE Vickers
OD Heslop
MF Smikle
e-Published: 17 Oct, 2013

Clinical and Laboratory Features of Youth Onset Type 2 Diabetes in Jamaica

Issue: 
Vol 59, issue 2 (2010)
Pages: 
131–8
Synopsis: 
Patients from two tertiary referral hospitals were assessed to determine whether Type 2 diabetes mellitus was present in Jamaican diabetic youth. Type 2 diabetes accounted for 22% of cases. Obesity was the most important clinical predictor of Type 2 diabetes.

ABSTRACT

Objectives: To assess the frequency of youth onset Type 2 diabetes mellitus (T2D) in Jamaica and the characteristics of youth with this form of diabetes.

PDF Attachment: 
PDF icon dr_mk_tulloch-reid_wimj.qxd_.pdf
Journal Sections: 
Original Articles
Keywords: 
Caribbean
diabetes mellitus
Adolescent
young adult
classification
Journal Authors: 
MK Tulloch-Reid
MS Boyne
MF Smikle
EG Choo- Kang
RH Parkes
RAWright-Pascoe
EN Barton
RJ Wilks
DE Williams
e-Published: 02 Oct, 2013

Cardiovascular Risk Profile in Caribbean Youth with Diabetes Mellitus

Issue: 
Vol 58, Issue 3 (2009)
Pages: 
219–26
Synopsis: 
In this study, there was a high prevalence of cardiovascular risk factors in the patients studied regardless of their diabetes type. While patients with Type 2 diabetes mellitus were more obese and had higher blood pressure readings when compared with those with Type1 diabetes, their overall glucose control was better. Differences in lipid profile were no longer significant after adjusting for BMI.

ABSTRACT

Objective: To assess the effect of diabetes mellitus type on conventional and novel cardiovascular risk factors in patients, diagnosed with diabetes from two major referral hospitals in Jamaica, before age 25 years and with diabetes duration < 6 years.

PDF Attachment: 
PDF icon dr_mk_tulloch-reid.pdf
Journal Sections: 
Original Articles
Keywords: 
diabetes mellitus
Caribbean Youth
Cardiovascular
Journal Authors: 
MK Tulloch-Reid
MS Boyne
MF Smikle
EG Choo-Kang
RH Parkes
RA Wright-Pascoe
EN Barton
RJ Wilks
DE Williams
e-Published: 18 Sep, 2013

High Genetic Diversity in Human Immunodeficiency Virus – Type 1 in Jamaica

Issue: 
Vol 58, Issue 3 (2009)
Pages: 
195–200
Synopsis: 
Molecular analysis of 53 strains of human immunodeficiency virus type-1(HIV-1) from Jamaican patients revealed the presence of several subtypes and a high genetic diversity of the virus in Jamaica.

ABSTRACT

PDF Attachment: 
PDF icon dr_heslop.pdf
Journal Sections: 
Original Articles
Keywords: 
Jamaica
Genetic Diversity in HIV
human immunodeficiency virus – type 1
Journal Authors: 
OD Heslop
MF Smikle
NA Christian
KM Harvey
IE Vickers
JP Figueroa
SE Brown
CDC Christie
B Bain
EN Barton
e-Published: 18 Sep, 2013

Immunological Evidence Supporting the Use of Extracts From Boehmeria jamaicensis Urb for Treating the Common Cold and Sinus Infections

Issue: 
Vol 56, Issue 6 (2007)
Pages: 
487–90
Synopsis: 
Extracts of Boehmeria jamaicensis stimulated gamma interferon and may have implications for the treatment of the common cold.

ABSTRACT

PDF Attachment: 
PDF icon williams_immunological_evidence_supporting_the_use_extracts.pdf
Journal Sections: 
Original Articles
Journal Authors: 
LAD Williams
JU Igietseme
JA Whittaker
MF Smikle
YA Bailey-Shaw
EN Barton
e-Published: 04 Jul, 2013

Molecular Epidemiology of Methicillin Resistant Coagulase-negative Staphylococci Isolates from Blood Specimens at a Tertiary Hospital in the Caribbean

Issue: 
Vol 56, Issue 5 (2007)
Pages: 
464–5
Synopsis: 
Molecular epidemiological studies of Methicillin resistant coagulase-negative Staphylococci provide important information on its spread in healthcare facilities and the clinical significance in individual patients.

INTRODUCTION

PDF Attachment: 
PDF icon akpaka_molecular_epidemiology_of_methicillin_resistant.pdf
Journal Sections: 
Short Commentary
Keywords: 
Coagulase-negative Staphylococcus
Journal Authors: 
PE Akpaka
MF Smikle
e-Published: 03 Jul, 2013

Antinuclear Antibodies and HLA Class II Alleles in Jamaican Patients with Systemic Lupus Erythematosus

Issue: 
Vol 56, Issue 2 (2007)
Pages: 
130–3
Synopsis: 
A cross-sectional study in which DNA HLA typing methods were used to investigate the associations between HLA and class II alleles and the presence of systemic lupus erythematosus and antinuclear antibodies (ANA) in Jamaicans. The HLA associations with ANA were similar to those found in other ethnic groups, but no significant positive HLA association with SLE was found.

ABSTRACT

Objective: The relationship between human leukocyte antigens class II (HLA) and antinuclear antibodies
was investigated in Jamaican patients with Systemic Lupus Erythematosus (SLE).

PDF Attachment: 
PDF icon christian_antinuclear_antibodies_and_hla_class_ii_alleles.pdf
Journal Sections: 
Original Articles
Keywords: 
Systemic Lupus Erythematosus
Antinuclear Antibodies
HLA Class II Alleles
Journal Authors: 
N Christian
MF Smikle
K DeCeulaer
L Daniels
MJ Walravens
EN Barton
e-Published: 01 Jul, 2013

Paecilomyces lilacinus Fungemia in a Jamaican Neonate

Issue: 
Vol 55, Issue 5 (2006)
PDF Attachment: 
PDF icon jacksonpaecilomyces_lilacinus.pdf
Journal Sections: 
Letters to the Editor
Keywords: 
Paecilomyces lilacinus
Journal Authors: 
ST Jackson
MF Smikle
MG Antoine
GD Roberts
e-Published: 17 Jun, 2013

Pre-published Manuscript

This manuscript has been assigned to a volume and issue but has not yet been published. It is either being edited, typeset or is in the proof stage of publication.
In the pre-published stage, this manuscript may contain statements, opinions, and information that have errors in facts, figures, or interpretation. Any final changes in this manuscript will be made at the time of publication and will be reflected in the final electronic version of the issue. The editors and authors and their respective employees are not responsible or liable for the use of any such inaccurate or misleading data, opinion or information contained in the articles in this section.

Pages

Subscribe to RSS - MF Smikle

West Indian Medical Journal

Faculty of Medical Sciences,
The University of the West Indies,
Mona, Kingston 7
Tel: (876) 927-1214
Fax: (876) 927-1846
wimj@uwimona.edu.jm
Top of Page