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OD Heslop

Dengue Virus Serotypes in Jamaica, 2003−2007

Issue: 
Pages: 
114–9
Synopsis: 
A study of the dengue viruses that were in circulation showed that all 4 serotypes were in circulation during 2003–2007 and the most prevalent were dengue serotypes 2 and 4.

ABSTRACT

Background: Dengue virus (DENV) infection is increasing in prevalence and severity globally. The severity of dengue is influenced by several factors including the immune response, viral and host genetic factors.

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e-Published: 17 Oct, 2013

Molecular Epidemiology of Dengue in Jamaica Dengue Virus Genotypes in Jamaica, 2007

Issue: 
Pages: 
120–5
Synopsis: 
A study of dengue viruses that were in circulation in Jamaica in 2007 identified strains of DENV-1 genotype III, DENV-2 strains of the American, American-Asian and Asian genotypes while DENV-4 strains segregated into a separate clade from published reference sequences.

ABSTRACT

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e-Published: 17 Oct, 2013

Dengue HLA Associations in Jamaicans

Issue: 
Pages: 
126–31
Synopsis: 
The HLA dengue associations in Jamaicans differ from those found in other ethnic populations. While HLA-A *24 and – DRβ5* 01/02 were associated with having dengue, HLA-A *23, -CW*04, -DQβ*02, DQβ*03 and –DQβ*06 were protective.

ABSTRACT

Background: Polymorphisms in the human leukocyte antigen (HLA) genes might predispose certain individuals to dengue fever (DF) and the severe forms of the disease: dengue haemorrhagic fever/ dengue shock syndrome (DHF/DSS).

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e-Published: 17 Oct, 2013

High Genetic Diversity in Human Immunodeficiency Virus – Type 1 in Jamaica

Issue: 
Pages: 
195–200
Synopsis: 
Molecular analysis of 53 strains of human immunodeficiency virus type-1(HIV-1) from Jamaican patients revealed the presence of several subtypes and a high genetic diversity of the virus in Jamaica.

ABSTRACT

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e-Published: 18 Sep, 2013

Human Immunodeficiency Virus Type-1 (HIV-1) Subtypes in Jamaica

Issue: 
Pages: 
279–82
Synopsis: 
The majority of strains of HIV-1 isolated from HIV-1 infected individuals in Jamaica were found to be HIV- 1 subtype B. The less frequently found HIV-1 subtypes were C, D and E and some strains were untypable by the methods used.

ABSTRACT

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e-Published: 06 Jun, 2013
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