The HLA dengue associations in Jamaicans differ from
those found in other ethnic populations. While HLA-A
*24 and – DRβ5* 01/02 were associated with having
dengue, HLA-A *23, -CW*04, -DQβ*02, DQβ*03 and
–DQβ*06 were protective.
Background: Polymorphisms in the human leukocyte antigen (HLA) genes might predispose certain individuals to dengue fever (DF) and the severe forms of the disease: dengue haemorrhagic fever/ dengue shock syndrome (DHF/DSS).