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VB Sampson

Early Electron Transfer in Cytochrome c oxidase Occurs by a Chymotrypsin Type Relay

Issue: 
Pages: 
499–505
Synopsis: 
This computer based study leads to the conclusion that electrons arriving at the surface of cytochrome c oxidase migrate to the enzyme’s first active centre by a hydride ion relay system similar to that seen at the active site of chymotrypsin.

ABSTRACT

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e-Published: 20 Sep, 2013

Probing the Specifics of Substrate Binding for Cytochrome c Oxidase A Computer Assisted Approach

Issue: 
Pages: 
54–60
Synopsis: 
Transfer of electrons from ferrocytochrome C to cytochrome c oxidase is facilated by enzyme-substrate complexes stabilized by salt bridges. Computer simulations were employed to identify residues that participate in intermolecular salt bridges.

ABSTRACT

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e-Published: 17 Sep, 2013
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