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cytochrome c oxidase

Early Electron Transfer in Cytochrome c oxidase Occurs by a Chymotrypsin Type Relay

Issue: 
Pages: 
499–505
Synopsis: 
This computer based study leads to the conclusion that electrons arriving at the surface of cytochrome c oxidase migrate to the enzyme’s first active centre by a hydride ion relay system similar to that seen at the active site of chymotrypsin.

ABSTRACT

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e-Published: 20 Sep, 2013

Hydrogen/hydride Ion Relay – A Mechanism for Early Electron Transfer in Cytochrome c Oxidases

Issue: 
DOI: 
10.7727/wimj.2012.120
Pages: 
3–11
Synopsis: 
Cytochrome c oxidase (COX) employs electrons obtained from cytochrome c to reduce oxygen to water. Recently, we proposed that electrons travel from cytochrome c to CuA of COX, by a hydrogen/hydride ion relay. Now, on the basis of a similar computer study, we conclude that this hydride/hydrogen ion mechanism is common to other oxidases.

ABSTRACT

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e-Published: 09 Apr, 2013
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