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metformin

Effect of Linagliptin versus Metformin on Insulin Secretion, Insulin Sensitivity and Glucose Control in Subjects with Impaired Glucose Tolerance

Issue: 
DOI: 
10.7727/wimj.2015.586
Pages: 
149–153
Synopsis: 
In impaired glucose tolerance patients, administration of linagliptin during three months decreased glucose levels at 90 and 120 minutes after a 75-g oral dextrose load and area under the curve of glucose, meanwhile metformin just decreased insulin at 0 minutes.

ABSTRACT

Aim: To evaluate the effect of linagliptin vs. metformin on insulin secretion, insulin sensitivity and glucose control in patients with impaired glucose tolerance (IGT).

Accepted: 
07 Dec, 2015
PDF Attachment: 
Journal Sections: 
e-Published: 30 Mar, 2016

A Potential Role for the Antidiabetic Drug Metformin in the Treatment of Platinum Resistant Ovarian Cancer

Issue: 
DOI: 
10.7727/wimj.2015.456
Pages: 
674–78
Synopsis: 
The ability of metformin to enhance the cytotoxic profile of carboplatin in platinum resistant OVCAR3 ovarian cancer cells was evaluated alone and in the presence of the FAK inhibitor PF-5733228. Metformin significantly increased OVCAR3 sensitivity to both carboplatin and PF-573228.

ABSTRACT

Accepted: 
08 Sep, 2015
PDF Attachment: 
Journal Sections: 
Journal Authors: 
e-Published: 12 Feb, 2016
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