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Marijuana

Old Herb, ‘New’ Purpose: A Preliminary Analysis of Marijuana as a Medicine in Barbados

Issue: 
DOI: 
10.7727/wimj.2018.136
Pages: 
53-8
Synopsis: 
This article analysed the potential of Cannabis sativa as a medicine in Barbados.

ABSTRACT

Accepted: 
03 Jan, 2019
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e-Published: 25 Mar, 2019

Dosage and Conditioning Period Determine Reward or Aversion to Cannabis-induced Conditioned Place Preference in Sprague-Dawley Rats

Issue: 
DOI: 
10.7727/wimj.2017.185
Pages: 
523-8
Synopsis: 
The study demonstrated that a shortened conditioning period of 18 minutes in the conditioned place preference paradigm could induce significant delta-9-tetrahydrocannabinol (∆9-THC) reward at low doses, supporting the addictive potential of the psychoactive agent of marijuana. This is the first report of significant reward at a dose of 0.05 mg/kg of ∆9-THC in an animal model of addiction.

ABSTRACT

Objective: To assess the addictive potential of cannabis by investigating the motivational responses to low doses of delta-9-tetrahydrocannabinol (Δ9-THC) and a marijuana tea extract (MTE), and to determine if the length of the conditioning period in the conditioned place preference (CPP) paradigm influences reward or aversion to these cannabinoid preparations.

Accepted: 
23 Oct, 2017
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e-Published: 19 Dec, 2017

The Cannabinoids as Therapeutic Agents in the Management of Pain

Issue: 
DOI: 
10.7727/wimj.2017.192
Pages: 
576-80
Synopsis: 
This paper explored the suitability of naturally occurring and synthetic cannabinoids for pain management. The antinociceptive mechanisms identified for cannabinoids, relative to currently available analgesics, are promising in several cases, more so for chronic than for acute pain, where the potential remains hopeful but as yet unrealized.

ABSTRACT

Objective: This review focussed on the role of the endocannabinoid system in relation to pain transmission and modulation. Various facets of both naturally occurring and synthetic cannabinoids (CBs) were explored in an effort to ascertain their suitability in the treatment and management of pain.

Accepted: 
23 Oct, 2017
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Journal Sections: 
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e-Published: 26 Oct, 2017

Dosage and Conditioning Period Determine Reward or Aversion to Cannabis-induced Conditioned Place Preference in Sprague-Dawley Rats

DOI: 
10.7727/wimj.2017.185
Synopsis: 
The study demonstrated that a shortened conditioning period of 18 minutes in the conditioned place preference (CPP) paradigm can induce significant ∆9-THC reward at low doses, supporting the addictive potential of the psychoactive agent of marijuana. This is the first report of significant reward at a dose of 0.05 mg/kg ∆9-THC in an animal model of addiction.

  ABSTRACT                                                                                                                                     

Accepted: 
23 Oct, 2017
Journal Sections: 
Journal Authors: 
e-Published: 26 Oct, 2017

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Decriminalization of Marijuana: Is this a realistic public mental health policy for Jamaica?

Issue: 
Pages: 
367–70

ABSTRACT

Marijuana has potential benefits and adverse effects. Despite its popularity in Jamaica, decriminalization may not be possible given the international and regional obligations of Jamaica.

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e-Published: 31 Jan, 2014

Substance Use among University Students at the St Augustine Campus of The University of the West Indies

Issue: 
Pages: 
641–9
Synopsis: 
Substance use is a significant health risk, particularly among university students. This study assesses substance use at The University of the West Indies, St Augustine. We conclude that the extent and problems created by substance use are significant and recommend targeted interventions.

ABSTRACT

Objective: Substance use and abuse is a well known public health risk that peaks in persons between 18 and 25 years of age and is prevalent among university students. While this has been repeatedly documented in developed nations, there have been limited studies in the English-speaking Caribbean. This study therefore sought to assess the prevalence of alcohol, tobacco and marijuana use among university students in the English-speaking Caribbean and any associated risk factors.

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e-Published: 15 Oct, 2013

The Prevalence of Marijuana Smoking in Young Adults with Sickle Cell Disease: A Longitudinal Study

Issue: 
Pages: 
224–7
Synopsis: 
A history of marijuana smoking was common in young adults with sickle cell disease. Usage increased between 2000 and 2004, and was seldom for medicinal purposes.

ABSTRACT

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e-Published: 10 Jun, 2013
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