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O Evliyaoglu

Protective Effects of CAPE on Isoniazid and Rifampicin Induced Hepatic and Pancreatic Injury

DOI: 
10.7727/wimj.2015.561
Synopsis: 
This study investigated the protective effects of caffeic acid phenethyl ester (CAPE) against rifampicin-isoniazid induced hepatic and pancreatic toxicity in terms of histopathological deterioration, oxidative stress (paraoxonase-1, total antioxidant status, Total oxidant status) and biochemical parameters changes. The side effects of INH and RFP treatment on hepatic and pancreatic tissues may be prevented with CAPE.

ABSTRACT

Objective: To investigate the protective effects of against isoniazid (INH) and rifampicin (RFP)-induced hepatic and pancreatic damage.

Accepted: 
04 Jan, 2016
PDF Attachment: 
Journal Sections: 
e-Published: 30 Mar, 2016

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Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

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