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U Firat

Protective Effects of Caffeic Acid Phenethyl Ester on Isoniazid and Rifampicin-induced Hepatic and Pancreatic Injury

Issue: 
DOI: 
10.7727/wimj.2015.561
Pages: 
350-5
Synopsis: 
This study investigated the protective effects of caffeic acid phenethyl ester (CAPE) against rifampicin-isoniazid-induced hepatic and pancreatictoxicity in terms of histopathological deterioration, oxidative stress (paraoxonase-1, total antioxidant status, total oxidant status) and biochemical parameters changes. The side effects of isoniazid and rifampicin treatment on hepatic and pancreatic tissues may be prevented with CAPE.

ABSTRACT

Objective: To investigate the protective effects of caffeic acid phenethyl ester (CAPE) against isoniazid (INH)- and rifampicin (RFP)-induced hepatic and pancreatic damage.

Accepted: 
04 Jan, 2016
PDF Attachment: 
Journal Sections: 
e-Published: 30 Mar, 2016
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