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Acute lymphoblastic leukaemia

The Role of FLT3-ITD and CEBPA Mutations on the Prognosis of Acute Lymphoblastic Leukaemia in Turkish patients

DOI: 
10.7727/wimj.2015.446
Synopsis: 
In this article, we evaluated the prognostic value of FLT3-ITD and CEBPA mutations in ALL. We did not detect any relationship between FLT3-ITD and CEBPA mutations as prognostic factors. However, FLT3-ITD mutation may affect the response to chemotherapy.

ABSTRACT

Accepted: 
08 Sep, 2015
PDF Attachment: 
Journal Sections: 
e-Published: 11 Feb, 2016

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Evaluation of Health-related Quality of Life in Paediatric Patients with Acute Lymphoblastic Leukaemia

Issue: 
DOI: 
10.7727/wimj.2014.138
Pages: 
277–80
Synopsis: 
The Paediatric Quality of Life Inventory is a widely used instrument to measure paediatric health-related quality of life (HRQOL) in children. In this study, HRQOL scores were significantly lower in patients with acute lymphoblastic leukaemia than in healthy controls.

ABSTRACT

Accepted: 
12 Aug, 2014
PDF Attachment: 
Journal Sections: 
e-Published: 12 May, 2015

The Role of FLT3-ITD and CEBPA Mutations on Prognosis of Acute Lymphoblastic Leukaemia in Turkish patients

DOI: 
10.7727/wimj.2015.446

ABSTRACT

 

Introduction: Acute lymphoblastic leukaemia (ALL) is the most common malignancy in childhood. Although some prognostic factors have been defined to date, estimation of prognosis is currently not perfect. Previous studies have shown an association of FLT3 with poor prognosis and CEBPA mutation with the development of acute myeloid leukaemia (AML). Here we aimed to evaluate the prognostic value of FLT3-ITD and CEBPA mutations in ALL.

Accepted: 
08 Sep, 2015
Journal Sections: 
e-Published: 11 Feb, 2016

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

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