Efflux

Mutation and Efflux System are Responsible for Ciprofloxacin Resistance in Klebsiella pneumoniae

Issue:

Vol 67, Issue 3: 2018

DOI:

10.7727/wimj.2015.324

Pages:

226-8

Synopsis:

The results demonstrated that the main mechanism of ciprofloxacin resistance was via the AcrAB efflux system with a decrease of the level of minimal inhibitory concentration, but the other mechanism including mutation of gyrA and presence of quinolone resistance loci was also considerable.

ABSTRACT

Received:

23 Jun, 2015

Accepted:

24 Aug, 2015

Published:

22 Oct, 2018

PDF Attachment:

wimj-iss3-2018_226_228.pdf

Journal Sections:

Original Articles

Keywords:

Ciprofloxacin

Efflux

Klebsiella pneumoniae

Journal Authors:

e-Published: 10 Mar, 2016

Read more about Mutation and Efflux System are Responsible for Ciprofloxacin Resistance in Klebsiella pneumoniae

Meropenem Efflux in Pseudomonas aeruginosa at a Tertiary Care Hospital in Jamaica

Issue:

Vol 67, Issue 2: 2018

DOI:

10.7727/wimj.2016.022

Pages:

105-9

Synopsis:

This article examined efflux as a mechanism of carbapenem resistance in Pseudomonas aeruginosa isolates at a hospital in Jamaica. The study detected that 80% of the isolates tested had efflux as a mechanism of resistance to meropenem.

ABSTRACT

Objective: Several mechanisms account for carbapenem resistance in Pseudomonas (P.) aeruginosa which is an emerging problem at a tertiary care hospital (TCH) in Jamaica. The observed pattern of carbapenem resistance that results from efflux mechanisms is unique because it is specific to meropenem (MEM). Investigation of efflux as a mechanism of carbapenem resistance needed to be done as the information obtained could inform therapeutic and infection control strategies.

Received:

13 Jan, 2016

Accepted:

21 Jan, 2016

Published:

03 Jun, 2018

PDF Attachment:

wimj-iss2-2018_105_109.pdf

Journal Sections:

Original Articles

Keywords:

resistance