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AM Nicholson

Multidrug Resistant Organisms in the Intensive Care Unit of a Tertiary Care Hospital in Jamaica

DOI: 
10.7727/wimj.2018.089
Pages: 
Synopsis: 
This article looks at the detection of multidrug resistant (MDR) on clinical and non-clinical surfaces of the Intensive Care Units (ICUs) of a tertiary care hospital post detection of an outbreak or endemic strain of similar pathogens in patient samples. The aim was to highlight the potential role of the environment as a possible reservoir for organisms and underscore the importance of infection control strategies in breaking the chain of infection.

ABSTRACT

Objective: The aim of this study was to determine the presence of multidrug resistant (MDR) pathogenic bacteria in the environment of the Intensive Care Units (ICUs) a tertiary care hospital in Jamaica.  This was done to find out if organisms previously associated with outbreaks are present and to make recommendations as appropriate, for infection prevention and control measures.

Accepted: 
15 Jun, 2018
PDF Attachment: 
Journal Sections: 
e-Published: 27 Feb, 2019

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

Meropenem Efflux in Pseudomonas aeruginosa at a Tertiary Care Hospital in Jamaica

Issue: 
DOI: 
10.7727/wimj.2016.022
Pages: 
105-9
Synopsis: 
This article examined efflux as a mechanism of carbapenem resistance in Pseudomonas aeruginosa isolates at a hospital in Jamaica. The study detected that 80% of the isolates tested had efflux as a mechanism of resistance to meropenem.

ABSTRACT

Objective: Several mechanisms account for carbapenem resistance in Pseudomonas (P.) aeruginosa which is an emerging problem at a tertiary care hospital (TCH) in Jamaica.  The observed pattern of carbapenem resistance that results from efflux mechanisms is unique because it is specific to meropenem (MEM).  Investigation of efflux as a mechanism of carbapenem resistance needed to be done as the information obtained could inform therapeutic and infection control strategies.

Accepted: 
21 Jan, 2016
PDF Attachment: 
Journal Sections: 
e-Published: 01 Mar, 2016

Detection of OXA Carbapenemase Positive Acinetobacter spp., Jamaica

DOI: 
10.7727/wimj.2016.065
Synopsis: 
This article looks at the mechanism of carbapenem resistance and clonality of multidrug resistant Acinetobacter spp. at a hospital in Jamaica. PCR found that many of these isolates, some of which are clonally related, were carbapenemase producers.

ABSTRACT

Objective:  The global problem of resistance to carbapenem antibiotics, through the production of carbapenemases by clinically significant bacteria, continues to increase while options for antibiotic therapy remain limited. It is important to determine the mechanism of carbapenem resistance in the multidrug resistant (MDR) Acinetobacter spp.  isolated at a tertiary care hospital, Jamaica (TCHJ) because of the implications for therapy which is the goal of this study.

Accepted: 
20 Apr, 2016
PDF Attachment: 
Journal Sections: 
e-Published: 27 Apr, 2016

Disclaimer

Manuscripts that are Published Ahead of Print have been peer reviewed and accepted for publication by the Editorial Board of the West Indian Medical Journal. They may appear in their original format and may not be copy edited or formatted in the style guide of this Journal. While accepted manuscripts are not yet assigned a volume, issue or page numbers, they can be cited using the DOI and date of e-publication. See our Instructions for Authors on how to properly cite manuscripts at this stage. The contents of the manuscript may change before it is published in its final form. Manuscripts in this section will be removed once they have been issued to a volume and issue, but will still retain the DOI and date of e-publication.

The Detection of Mupirocin Resistance and the Distribution of Methicillin-resistant Staphylococcus aureus at the University Hospital of the West Indies, Jamaica

Issue: 
Pages: 
509–13
Synopsis: 
Methicillin-Resistant Staphylococcus aureus is an important cause of nosocomial infection. Nasal carriage plays an important role in its spread and is usually treated by topical mupirocin. The emergence of mupirocin resistance is significant since it is one of the few topical antimicrobial agents shown to be safe and effective.

ABSTRACT

Objectives: The objectives of this study were to determine the susceptibility of Methicillin Resistant Staphylococcus aureus (MRSA) isolates to Mupirocin and other antimicrobial agents and to record the prevalence and distribution of this organism at the University Hospital of the West Indies (UHWI).

PDF Attachment: 
Journal Sections: 
e-Published: 15 Oct, 2013

Predictors of Poor Outcome in Neonates with Bacterial Sepsis Admitted to the University Hospital of the West Indies

Issue: 
Pages: 
80–4
Synopsis: 
Prematurity, very low birthweight and female gender are predictors of poor outcome in neonates with bacterial sepsis. Strategies aimed at decreasing morbidity and mortality in neonates with sepsis must include measures that will decrease the incidence of prematurity and low birthweight.

ABSTRACT

PDF Attachment: 
Journal Sections: 
e-Published: 10 Jun, 2013

Whipple's Disease in an Afro-Caribbean National

Issue: 
DOI: 
10.7727/wimj.2012.220
Pages: 
101–4

 ABSTRACT

Accepted: 
25 Jul, 2012
PDF Attachment: 
Journal Sections: 
e-Published: 06 Jan, 2014

The Changing Pattern of Tinea Capitis in Jamaica

Issue: 
Pages: 
85–8
Synopsis: 
Tinea Capitis infection may be rising in Jamaica with a preponderance of Trichophyton tonsurans infection.

ABSTRACT

PDF Attachment: 
Journal Sections: 
e-Published: 10 Jun, 2013

Distribution of Nosocomial Organisms and their Resistance Patterns in the Intensive Care Unit of the University Hospital of the West Indies, Kingston, Jamaica

Issue: 
Pages: 
142–8
Synopsis: 
This information would guide empiric therapy as well as infection control measures.

ABSTRACT

Objectives: To determine the distribution and antibiotic susceptibility patterns of nosocomial pathogens in the Intensive Care Unit (ICU) at the University Hospital of the West Indies (UHWI).

PDF Attachment: 
Journal Sections: 
e-Published: 18 Sep, 2013
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